TIOPROPERAZIN (Thioproperazinum). Dimetilsulfamido-10- 2-[3-(1-methyl-4 piperazinil) - propyl] - fenotiazin.

     Issued by : dimetansulfonata.

     Synonyms : Mazheptil, Cephalin, Majeptil, Thioperazine, Vontil.

     On chemical structure differs in the presence of 2 fenotiazinovogo kernel dimetilsulfamidnoy group instead of chlorine atom from meterazina and triftormetilnoy group of triftazina.

     Has strong protivorvotnoe action has sedative effect of the weak, poorly potentsiruet of hypnotics and analgesics, adrenoliticheskoe has little effect.

     Strong antipsihoticheskoe combined with a stimulating effect (rastormazhivayuschim), clinically manifested motor hyperactivity.

     The drug is effective in gebefrenicheskoy and continuously leaking katatonicheskoy forms of schizophrenia, and other forms of schizophrenia with a progressive period.

     Assign inside after eating and intramuscularly. Initial dose-0,001 0,005 - 0.01 g (1-5 - 10 mg) per day with a gradual increase to 0,05 - 0,06 g (50-60 mg) per day for 3 to 4 admission. If necessary daily dose increased to 0.1 - 0.15 g. reach therapeutic effect dose gradually.

     Intramuscularly imposed from 0.0025 g (2, 5 mg) to 0,06 - 0,08 g (60-80 mg) a day.

     During treatment can be observed phenomenon parkinsonizma, akatiziya, okulogirnye crises, insomnia, palliative, salnost person sweating, menstrual irregularities.

     The drug is not suitable for organic diseases of CNS. Be wary when designate diseases of liver, kidneys and the cardiovascular system under decompensation.

     Method of issuance : pills to 0,001 g (1 mg) and 0.01 g (10 mg); 1% solution in ampoules and 1 ml (10 mg).

     Storage : List B. In the dark spot.

Materials allowed to copy only with the active hyperlink to the handbook of medicines