Theobromine (theobrominum)


TEOBROMIN (Theobrominum). 3, 7-Dimetilksantin. Alkaloid, extracted from the seeds of cocoa husk (Semina Sasao). There is also a synthetic way.
     Synonyms : Theostene, Thesal.
     The white crystalline powder bitter taste. Very little is soluble in cold water (1 : 700), little in the hot, easy-to divorced alkali and acid.
     On chemical structure and pharmacological properties similar to other alkaloids purinovogo series. It has a stimulating effect on the heart functions, increases coronary heart vessels and bronchi mocheotdelenie increases. Diuretichesky effect is linked mainly to a decrease kanaltsevoy reabsorption of water, sodium and chlorine ions. Relatively with caffeine Theobromine is a weak central nervous system excitation.
     Applied mainly nerezko expressed cramps cerebrovascular accidents, sometimes swelling due to heart and kidney failure.
     Included in the combined number of tablets. Earlier vypuskavshiysya drug "Temisal" (T hemisalum; Shortcut - Dauretin), a combination teobromina with musk and sodium used as a diuretic and moderately active sosudorasshiryayuschego funds recently removed from the range of drugs (due to the low efficiency and lack of stability) .
     Method of issuance : powder; Tablets of 0.25 g; The combined regimen containing : a) teobromina dibazola 0.25 g and 0.02 g; B) teobromina 0.25 grams and 0.02 grams of phenobarbital, as well as pills "Teminal "" Teoverin, Teodiba Verin.
     Pills "Teminal (Ta bulett s" T h e minalum ") contain teobromina and amidopirina of 0.25 grams of phenobarbital and 0.02 g.
     Pills "Teoverin (Ta bulettae" T h e rinum fee v) contain teobromina 0.25 g, 0.03 g papaverina hydrochloride and barbamila 0,075 g.
     Pills "Teodibaverin (Ta bulettae" T heodibaverinum ") contain teobromina 0.15 g papaverina hydrochloride and dibazola to 0.02 g.
     All tablets appoint 2 - 3 times a day (one pill to receive).
     Storage teobromina and its combined pill containing : List B.
     R p. : Ta b. T h fee bromini 0.25 N. 10
     D.S. At one tablet three times a day (after eating)
     R p. : Tab. "T heoverinum" N. 10
     D.S. At one pill 2 - 3 times a day
     R p. : Ta b. T h fee dibaverinum "N. 10.
     D.S. At one tablet three times a day
     Previously issued pill "Teodinal (T heodinalum") containing 0.25 g teobromina, dibazola and 0.02 grams of phenobarbital, excluded from the range of medicines.

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