TERAZOZIN (Terazosin).

     1-(4-Amino-6, 7-dimetoksi-2- hinazolinil) -4 - (tetragidro-2- furoil) piperazine hydrochloride.

     Synonyms : Kornam, Setegis, Haytrin, Cornam, Hytrin, Setegis.

     The white crystalline powder. Well soluble in water.

     On chemical structure very close to prazozinu differs only in the replacement cycle tertrahydrofuran furan.

     Long blocks postsinapticheskie A1- adrenoretseptory receptacles prostate gland and bladder.

     Quickly and completely absorbed in the digestive tract, bioavailability greater than 90%, with max of 1 hour, T1 / 2 to 12 h, and therefore drug designate one every day; Biotransformation exposed in the liver, allocated mainly to feces.

     Applied to treat arterial gipertenzy sound hyperplasia and prostate gland (see Prazozin).

     With arterial hypertension appoint from 0,001 g (1 mg) into the night (down), then gradually increase the dose to 0,005-0,01 g (5-10 mg) a day, monitoring performance and portability .

     In the isolationist prostate gland also appointed first dose of 0,001 grams (1 mg) at night, then 0,002-0,01 g (2-10 mg) a day.

     Possible side effects, and precautions such as when applying prazozina.

     Product : pills to 0,001; 0,002; 0.005 and 0.01 g (1; 2; 5; , And 10 mg) (N. 10, 20, 28).

     Storage : List B.

Materials allowed to copy only with the active hyperlink to the handbook of medicines