TELMISARTAN (Telmisartan).

     4? Metil-6--[(1-methyl benzimidazolil) -2 - propil-1- benzimidazolil] -2 - bifenilkarbonovaya acid.

     Synonyms : Mikardis, Praytor, Micardis, Prytor.

     White or colourless crystalline powder. Virtually no soluble in water, partially soluble in strong acid and soluble in strong alkali.

     Well absorbed in the digestive tract, bioavailability of 40-60% (effect "first pass" through the liver), C max, 1 h, T? 20-30 h; displayed mostly with bile.

     Applied with arterial hypertension.

     Assign inside of 0.04 g (40 mg), as appropriate 0,08 g (80 mg) 1 every day.

     Antihypertensive effect evolved through three hours after admission and continued for more than 24 hours; Stable clinical effect is achieved through a 4-8 week course of treatment.

     Side effects (headache, dizziness, neuralgia, nausea, diarrhea, cough, pain in the abdomen, chest and back, giperurikemiya, etc.) are rare.

     The drug is not suitable for serious violations of the liver and kidney in pregnancy and breastfeeding.

     Product : pills to 0.04 and 0.08 g (No. 7, 14).

     Storage : List B.

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