TAMSULOZIN (Tamsulosin).

 

     5-[2-[[2 - (ortho Etoksifenoksi) ethyl] amino] propyl] -2 - metoksibenzolsulfonamida hydrochloride.

     Synonym : Omnik, Omnic.

     The structure differs from prazozina and its analogs lack fragments hinazolinila and furan, but also possesses the election A1- adrenoblokiruyuschey activity shown mainly on the relevant receptors prostate gland, bladder neck and orprostate part of the urethra. In therapeutic doses does not significantly affect the AC adrenoretseptory receptacles.

     Completely absorbed in the digestive tract, bioavailability reaches 100%, S max is 6 h, T1 / 2 to 10 h; Slowly metabolised in the liver, kidneys displayed mainly in the form of metabolites.

      Is in the prostate gland hyperplasia good inside to 0.4 grams (one capsule) morning (after breakfast), heavy squeezed water.

     Usually drug well tolerated. Possible side effects and precautions are basically the same as when applying prazozina and its analogs.

     Method of issuance : capsules to 0.4 mg (N. 10, 30).

     Storage : List B.

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