SULTOPRID (Sultopride).

     N-[(-1 - Ethyl temperatures) methyl] -5 - (etilsulfonil) -2 - metoksibenzamid.

     Synonyms : Barnetil, Topral, Barnetil, Topral.

     On the chemical structure and action close to sulpiridu. Instead amino (with sulfonilnoy group) contains ethyl substituent.

     Has antipsihoticheskoe, sedate and blood effects.

     Neurotic effects associated with the blockade D2- dofamine receptors brain. Has moderate antiserotoninovuyu and katoleptogennuyu activity.

     Once inside absorbed quickly and completely, bioavailability of 80-90%, S ma x-0,5-2 hour, T1 / 2-hour 3-5, provides kidney unchanged.

     Applied with psychosis and chronic alcoholism for the treatment of edema and aggressiveness and excitation.

     Assign inside and intramuscularly.

     Inside appointed from 0.4 to 1.6 g / day (1-4 times daily), with the improvement in the lower dose to 0,4-0,6 g per day.

     When delusional state and to initiate edema impose intramuscularly to 0,4-1,2 g / day (maximum daily dose of 1.6 g).

     The drug used only in a hospital.

     Possible side effects : extrapiramidale disorders, loss of appetite, diarrhea, drowsiness, aetiology, Orthostatic Hypotension, giperprolaktinemiya, Galactorrhea, amenorrhea, Bitch, impotence, in long-term use of high-dose depression convulsant syndrome.

     The drug is contraindicated in aetiology, feohromotsitome, gipokaliemii.

     Caution must be exercised with epilepsy, parkinsonizme, severe cardiovascular disease.

     Deprimiruyuschie enhance the effects of narcotic analgesics, barbiturates, tranquilizers, alcohol, and weakens protivokashlevyh - levodopa. Side effects sultoprida exacerbate antidepressant drugs, fenotiazinovye preparations antigipertenzivnye funds (including B-adrenoblokatory and clonidine), heart diseases and complications products I and III classes gipokaliemiya.

     Method of issuance : pills to 0.4 g (N 10, 20, 100); 10% injection of 2 ml ampoules.

Materials allowed to copy only with the active hyperlink to the handbook of medicines