SULPIRID (Sulpiride).

     N - (1-Ethyl 2 pirrolidinilmetil) - 2-metoksi-5- sulfamoilbenzamid.

     Synonyms: Dogmatil, Eglonil, Abilit, Digton, Dobren, Dogmalid, Dogmatil, Eglonyl, Eusulpid, Lisopiride, Megotyl, Miradon, Mirbanil, Modulan, Nivelan, Norestran, Omperan, Sulpiril, Suprium, Sursumid, Tepavil, Tonofit, Trilan, Ulceridol, Ulpir, Vipral and others.

     Sulpiride is derived sulfonilbenzamida. This same group tiaprid and some other psychotropic funds. By building and some pharmacological properties Sulpiride also close to metoclopramide (see).

     Like metoclopramide has protivorvotnoe effect; Moreover, it has pharmacological properties characteristic of psychotropic drugs; Having moderate and antiserotoninovoe kataleptogennoe effect, several fenamina weakens the incentive effects. Sedative action is not without increased power and analgetikov barbiturates. Protivosudorozhnoy activity is not.

     Sulpiride is clinically characterized as a product of <governing> impact on TSNS whose moderate adjunct activity coupled with some antidepressivnymi and stimulating properties. Adjunct effect, possibly because the product is dofaminovyh receptor antagonist.

     In psychiatric practice Sulpiride used mainly in combination with other drugs in the brain and the state, accompanied by weakness, slow, anergiey, including gallyutsinatorno- and delusional disorders (mainly repressive) disorders. As activator vehicle used in low schizophrenia. Assign inside 100-1000 mg per day. In severe cases, beginning with the introduction of the drug intramuscularly in doses of 100 to 800 mg per day.

     Sulpiride also apply to migraine, golovokruzheniyah, violations of conduct in children. In these cases, designate an adult inside the 100-300 mg / day; Children 5 mg / kg per day.

     In connection with antiemetics and <tsitoprotektornym> on the mucosal lining of the stomach (see Metoklopramid), and <governing> impact on the nervous system when used Sulpiride stomach ulcer disease and stomach cancer. Immediate action antatsidnym product is not. Typically used in the face of the diet therapy. Usually appointed interior, starting with doses of 200 mg / day (100 mg two times a day, morning and evening), increasing the need for a daily dose of 400 mg (200 mg 2 times a day).

     The product can be injected intramuscularly.

     Sulpiride is usually well tolerated by. There may, however, be observed pyramid violations arousal violation of sleep, increased AD, menstrual irregularities; Described cases galaktorei and ginekomastii.

     The product contraindications patients with feohromotsitomoy and expressed hypertension. Do not appoint Sulpiride patients in a state of anxiety and psychomotor stimulation.

     Method of issuance: capsules containing 50 mg of the drug in the package of 30 capsules; 5% solution in ampoule of 2 ml (100 mg vials) in the package to 6 vials; 0.5% solution in vials of 200 ml (25 mg at tea spoon); tablets of 0.2 g 200 mg <<Eglonil Fort>> in the package of 12 pieces.

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