SULFALEN (Sulfalenum). 2 - (para-Aminobenzolsulfamido) -3 - metoksipirazin.

     Synonyms : Kelfizin, Dalysep, Kelfizina, Longum, Polycidal, Sulfalene, Sulfamethoxypyrazine, Sulfametopyrazine, Sulfapyrazinmethoxin.

     White or white with a yellowish sheen crystalline powder. Almost nerastvorim water, easily soluble in acid and alkali solutions.

     For antimicrobial action sulfanilamidnym close to other drugs. There are, however, having <<sverhdlitelny>> effect.

     Once inside rapidly absorbed, the maximum concentration in the blood is found through 4-6 hours Diluted long circulates in the blood. The half of the blood averaged 65 h; 60% imposed dose displayed during the nine days. The slow withdrawal of the organism due to the low reabsorption in the renal drug Channel.

     Sulfalen well into the body fluids and tissues. In high concentrations found in bile. Preparation is less than other depot sulfanilamidy, associated plasma protein that ensures its high concentration in the blood of active free form.

     The drug in dosage does not affect kidney function (no kristallurii).

     Assign sulfalen with infectious diseases caused by susceptible to microbial drugs sulfanilamidnym : infection of the respiratory system (bronchitis, and pneumonia focal pneumonia, bronchial and others), a pot (cholecystitis, holangit), the urinary tract (pielit, anesthetic, filter, etc.) ; various sites purulent infection (Wound infections, abscesses, mastitis, etc.); with bullet, otitis, sinusitis, etc. can be used in combination with antimalarial drugs (see Hloridin, Sulfapiridazin) with malaria (especially in forms that are resistant to monotherapies ), and toxoplasmosis.

     In dysentery sulfalen apply impractical because of the received inside in small doses, it is rapidly absorbed from the small bowel, and therefore does not provide any concentration in the gut.

     Assign sulfalen inside day or one every 7 -10 days. Every day, mostly with severe infection or high-speed, 1 in every 7 to 10 days for chronic, long-term recurrent infection and prevent long (with Rheumatoid disease, chronic bronchitis, etc.).

     Daily use of designated adults in Day 1 of 1 g, and then to 0.2 grams per day. Recreation for 30 minutes before eating.

     When taken one every 7 - 10 days to appoint an adult dose of 2 grams off

     Duration of treatment is usually 7 to 14 days. If within 14 days the effect is not evident, and thus medication used for treatments.

     Given the slow down of a drug should not exceed the specified doses.

     In the case of a drug for the prevention of relapse (for chronic lung disease, rheumatism, kidney disease and urinary tract) appoint 2 g (adults) 1 week. Treatment may continue (with good endurance) to a 1 - 1, 5 months.

     Sulfalen generally well tolerated, but may nausea, allergic reactions, headaches, radiation. When expressed adverse drug events cancelled.

     Contraindications to the use sulfalena serve in a history of allergies MEPhI admission sulfanilamidnyh drugs azotemiya, pregnancy. Patients who are in violation of renal excretory function sulfalenom treatment to control blood and urine tests.

     Product : 0.2 grams of pills in a package of 30 pieces.

     Storage : List B.

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