Sulfadimezin (sulfadimezinum)


SULFADIMEZIN (Sulfadimezinum). 2 - (para-Aminobenzolsulfamido) - 4, 6-dimetilpirimidin.
     Synonyms : Diazil, Diazol, Dimethazil, Dimethyldebenal, Dimethylsulphadiazine, Dimethylsulphapyrimidine, Pirmazin, Sulfadimerazine, Sulfadimidine, Sulfadimidinum, Sulfamethazine, Sulfamezathil, Sulfamezathine, Sulmet, Sulphadimethylpyrimidine, Sulphadimidine, Superseptyl.
     The white or slightly yellow crystalline powder. Almost nerastvorim water, easily soluble in acid and alkali.
     Applied with pneumococcal, streptococcal, meningococcal infections, sepsis, gonorrhea, and infections caused by coliform bacilli and other microorganisms.
     Sulfadimezin rapidly absorbed, about malotoksichen.
     Doses for adults are the same as norsulfazola doses.
     Higher dose for adults inside a single 2 g daily 7 g.
     Children designate 0.1 g / kg for the first reception, then 0,025 g / kg every 4-6 - 8 hours
     When treating dysentery sulfadimezin designate an adult as follows : 1 st and 2 nd day of illness for six grams a day (every 4 h 1 g); In the third and 4 th day-to 4 grams per day (every 6 h and 1 g); 5 th and 6 th days to 3 grams a day (every 8 h 1 g). On treatment of 25 to 30 g drug. After 5 - 6 days a second round of treatment : in the 1 st and 2 nd days appoint 1 g at 4 h (night through 8 h), all of 5 grams a day; In the third and 4 th days for every 1 g 4 h (at night do not), all of 4 g / day; a 5-day-1 through 4 g h (at night do not), only 3 grams per day. During the second cycle provides 21 grams of preparation; With minor illness dose can be reduced to 1918
     Children with dysentery sulfadimezin designate in the following doses up to 3 years up to 0.2 g / kg per day; The daily dose divided into four reception and gave during the day, disrupting nighttime sleep. That dose of medication taken for 7 days. Children aged 3 years appoint four times daily in a single dose of 0.4 to 0.75 grams, depending on age.
     Sulfadimezin as other sulfanilamidnye drugs are often used in conjunction with antibiotics.
     Combined with hloridinom sulfadimezin apply to toxoplasmosis.
     When treating sulfadimezinom designate plenty alkaline water. It systematic study of blood, as in the treatment of other sulfanilamidnymi drugs.
     Method of issuance : powder; Tablets of 0.25 and 0.5 g in a package of 10 pieces.
     Storage : List B. The well ukuporennoy packaging keeps from the world.

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