STREPTOTSID (Streptocidum). Aminobenzolsulfamid parameters.

     Synonyms : Streptotsid white Ambesid, Deseptyl, Dipron, Prontalbin, Prontalin, Prontoin, Prontosil album, Streptamin, Streptocidum album, Streptozol, Sulfamidyl, Sulfanilamide, Sulfanilamidum, Sulphanilamide and others.

     The white crystalline powder and odourless. Little is soluble in water (1:170), easy-to boiling water, it is difficult to alcohol (1:35), soluble in solutions caustic alkalis.

     Has antimicrobial action against the streptococcal, meningococcal disease, gonokokkam, pneumococcal, coliform bacillus, and some other bacteria.

     With the organism streptotsid rapidly absorbed. The highest concentrations of the drug in the blood through a 1 - 2 h after administration. After 4 h, it is found in the spinal fluid. There were predominantly (90-95%) kidneys.

     Streptotsid applied for the treatment of angina, rozhistogo inflammation, cystitis, pielita, enterocolitis, for the prevention and treatment of wound infections and other infectious diseases.

     Assign an adult on the inside of 0,5-1, 0 g 5 - 6 times a day, just a day, 3 to 6 g; Children under 1 year of 0.05-0.1 g / reception from 2 to 5 years for 0.2 - 0.3 grams, from 6 to 12 years - to 0.3 - 0.5 g. The unconscious and vomiting can be replaced by the appointment of the drug inside the introduction of the muscle under the skin or in veins streptotsida soluble.

     Higher doses for adults inside : single 2 g daily 7 g.

     In infectious diseases surface skin and mucous membranes the nose and ear, and burns, ulcers, etc. apply streptotsid of masi (10%) or linimenta (5%). With deep wounds, streptotsid made into a wound as thoroughly crushed prosterilizovannogo powder (5 - 10 - 15 g); Once appointed sulfanilamidnye (or other antimicrobial) drugs inside.

     In mixture norsulfazolom, penicillin and ephedrine, streptotsid sometimes used for acute rhinitis; Vduvayut powder in the nose cavity with a special poroshkovduvatelya or sucked into the nose, with breath (see also Maze <<Sunoref>>).

     Before streptotsida sometimes occur headache, dizziness, nausea, vomiting; Cyanosis can develop.

     Admission large quantities of the drug can cause changes in the blood system (radiation, agranulotsitoz), sometimes nervous and cardiovascular systems (parestezii, tachycardia), and dermatitis, diarrhea. In urinary apparatus admission streptotsida complications are rare.

     Recently, instead streptotsida increasingly apply sulfadimezin, etazol and better sulfanilamidnye drugs that cause fewer side effects.

     Contraindications to treat disease are streptotsidom haematopoietic system, principally, jade, Basedow's disease. In long-term care streptotsidom should periodically blood tests.

     Method of issuance : powder; Tablets of 0.3 and 0.5 grams in a package of 10 pieces; 10% ointment; 5% Liniment.

     Storage powder and tablets : List B. The well ukuporennoy packaging.

     Ointments streptotsidovaya (Unguentum Streptocidi). Contains 10 g and 90 g streptotsida vaseline (100 g, 10% of masi). Ointments svetlozheltogo white or color.

     Applied to treat wounds, sores, burns, fractures, and piodermii etc.

     Available in glass for banks of 30 g.

     Store in a cool place protected from the light.

     Liniment streptotsida 5% (Linimentum Streptocidi 5%). Ingredients : streptotsida 5 g, 34 g of fish oil, emulsifier, stabilizer and distilled water to 100 g.

     Thick smetanoobraznaya homogeneous mass burovato- amber or yellow to a specific smell.

     Local applied in the treatment of wounds festering, infected burns rozhistogo inflammation and other chronic inflammatory processes. Apply directly to the skin surface or aloe to marlevuyu towel. Tubal produce 1 to 2 days.

     Store in a cool, the dark spot in the tightly closed glass banks. In the case of storage burovatoy film on the surface linimenta (fat oxidation products), remove the film, after which you can apply Liniment.

     Product : Banks in glass tubes of 30

     Rp. : Tab. Streptocidi 0.3 N.10

     D.S. On February 5 - 6 tablets per day

     Rp. : Lin. Streptocidi 5 30.0%

     D.S. For lubricating skin (with scalding)

     Ointments <> (<C unoref> Unguentum <<Sunoreph>>). Ingredients : streptotsida 5 g 5 g norsulfazola, sulfadimezina 5 grams of ephedrine hydrochloride 1 g, 0.3 g camphor, eucalyptus oil 0.39 g, vaseline to 100 g. Available in glass tubes or banks of 15 g.

     Applied locally (lubricating mucous membranes nose) for the treatment of acute and chronic rinitov.

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