Spazmolitin (spasmolytinum)


SPAZMOLITIN (Spasmolytinum). ~ Dietilaminoetilovogo ether-1, 1-difeniluksusnoy hydrochloride acid.
     Synonyms : Difatsil, Adiphenin, Trasentin, Vagospasmyl, Veganthin.
     The white crystalline powder solonovato- bitter taste. The easily soluble in water. In dry racks, aqueous solutions gradually gidrolizuyutsya,
     Has m holinoliticheskoy peripheral activity; Moreover, having a blocking effect on the n-holinoreaktivnye system. Has spasmolytic activity : relaxes smooth muscles of internal organs and blood vessels; Is the local anaesthesia.
     When applied pilorospazme, spastic cramps, zhelchnokamennoy disease, renal colic, gastric ulcer and duodenal ulcers, with strokes, endarteriite, and the chamber, neuritis radiculitis. There is evidence of the effectiveness of the drug in zudyaschih Medicine, as well as migraines.
     Assign spazmolitin inside after eating at 0.05-0.1 g 2 - 3 - 4 times a day. The course of treatment 3 to 4 weeks.
     In applying spazmolitina (as well as other holinolitikov) individually select dose. In overdose can be dizziness, headache, a feeling of intoxication (at the central act), dry mouth (for the peripheral cholinolytic action), a violation of accommodation.
     While irritating effect on the mucous membrane of the stomach, spazmolitin can cause diarrhoeal phenomenon.
     The sense of intoxication and dizziness can be prevented or reduced supplies caffeine (0.1 - 0.2 g sodium benzoate kofein- inside or 1 ml 20% solution under the skin).
     Spazmolitin and close to the preparations (arpenal, etc.) should not be taken before and during transport drivers and others whose jobs require rapid mental and physical reactions.
     Contraindicated in glaucoma.
     Product : powder.
     Storage : List B. In dry, the dark spot.
     Abroad, called Neuro- T rasentin "issued tablets containing 0.03 g trazentina (spazmolitina) and 0.04 grams of phenobarbital. Applied as a sedative and holinoliticheskoe funds (with nervousness, increased excitability, treatment of functional gastrointestinal tract).

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