SOMATOTROPIN (human) (Somatotropinum humanum).

     Pituitary Hormone front of people.

     Synonyms : Growth Hormone, Somatropin, Humatrop, Asellacrin, Crescormon, Genotropin, Humatrop, Nanormon, Somatonorm, STH, Somatropin.

     Polypeptid is composed of 191 amino acid balance.

     Has anabolic effect, a positive impact on mineral exchange, increases growth and body mass in the dwarf, with growth hormone deficiency.

     In the past, for medical applications issued somatropin for injection released from gipofizov.

     More recently (1998) the drug removed from the range and replaced drugs somatotropina obtained by means of genetic engineering (Sayzen, Genotropin, Humatrop, Norditropin, etc.).

     Testimony to use drugs somatotropina violations development organism associated with growth hormone deficiency (hypophyseal dwarfism, hypophyseal nanizm).

     Priparaty not receive the group with malignant tumors.

     Sayzen (Saizen).

     Growth hormone, obtained by genetic engineering (using animal cells mammals).

     It is a matter of growth and body mass index (mainly in patients with delayed growth of violations of endogenous growth hormone secretions).

     Indications for use-see Somatotropin.

     Enter subcutaneously or intramuscularly. Daily applied at the rate of 12 ED (IU) per 1 square. M surface of the body (0.6 U / kg). In the absence of effective dose increased to 20 ED / sq. km. M (0,8 or ED / kg).

     In a raschinanuyu weekly intramuscular dose share by 3 single injection (4 ED / sq. km. 0.2 m or ED / kg) and enter through the day (usually evening).

     In a weekly subcutaneous dose divided into single doses of 6-7.

     Treatment for a long-term (under close clinical and laboratory controls).

     There are indications that, after 12 months of sayzena there has been a significant increase in the rate of growth in children.

     Product : dried powders in vials on April 10 or IU.

     Storage : at temperatures from 2 to 8 C (in the refrigerator).

     Genotropin (Genotropin).

     Variety rekombinatnogo (available genetically engineered using Escherichia coli) somatotropina.

     Indications for use-see Somatotropin.

     Enter into the skin. Dose choose individually. Usually applied at the rate of 12-16 IU per 1 square. M body surface or 0,5-0,7 1 mg per kg of body weight per week. This dose is divided by the inentsy 6-7 (1 time in Deni).

     Product : special two sections cartridges (rounds), in one section containing 16 IU dried powder somatotropina (genotropina), the other solvent. Enter pomoschiyu with special syringe.

     Humatrop (Humatrop) issued in vials of 4 IU (dried powder for injection), and 18 and 36 IU in the special drug form (cartridges to 3 ml).

     Norditropin (Norditropin), in bottles of 12 and 24 IU.

     Indications for use Sayzen-see.

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