Solyusurmin (solusurminum)


SOLYUSURMIN (Solusurminum).
     Dinatrievaya salt complex compounds and antimony pyatiosnovnoy glyukonovoy acid. Contains 21-33% antimony.
     White or white with a light yellowish sheen odourless powder.
     Mg in the water, education opalestsiruyuschih solutions. Almost nerastvorim of alcohol.
     Using a ready ampulirovannogo 20% aqueous solution (transparent liquid with a yellowish greenish white) with visceral leishmaniasis. It can be used for the treatment of cutaneous leishmaniasis, especially the chronic form tuberkuloidnoy.
     The preparation of a 20% solution is injected. Intradermal injections painful, sometimes there infiltrates. Enter into the skin only with failure to introduce non (no expressed superficial veins).
     In visceral leishmaniasis daily doses ranging from 0.1 to 0.15 g of the drug and dose-rate of 1, 4 to 1, 8 g; Dosage depends on the age and weight of patients.
     The total daily dose of 1 kg dose rate of 1 kg of body weight Age patient body mass sick patient, dry years, 20% solution, 20% solution of dry powder g ml powder g ml
     Up to 7 years 0.15 0.75 1 5 1 8 7 5 9 8 14 0.12 0.6 1 4 1 7 7 8 8 5
     Over 14 0.1 0.5 1 4 1 6 7 - 8
     The daily dose of introducing children to one reception in two adult admission (morning and evening).
     Injections are doing every day without interruption. Started in doses equal to approximately 1 / 3 of total daily therapeutic doses; Gradually (through 3 to 4 injections) dose increased to a full day. When slowly developing therapeutic effect and the deteriorating state of the patient, the daily dose can be increased after 7 - 8 injections : children up to 0.15 g (0.75 ml), vzroslymdo 0.12 g (0.6 ml) for 1 kg of body weight . In an earlier clinical recovery introduction solyusurmina can stop, continuing dispensary monitor patients within 2 to 4 months. When relapse treatment repeat.
     In solyusurmin cutaneous leishmaniasis designate in the following doses :
  Full Age daily intake Exchange daily intake of 1 kg per 1 kg of patient body weight patient body weight patient body weight patient years of dry 20% solution, 20% solution of dry powder g ml powder g ml
  Before 7 0.1 0.5 1 5 1 8 7 5 9 0 8 14 0.08 0.4 1 4 1 7 7 0-8 5 14 0.07 Over 0.35 1, 4, 1, 6, 7, 8, 0, 0
     Enter daily, choosing from 1 / 3 to 1 / 4 the total daily dose. Gradually (over 3 - 4 days) dose increased to a full day.
     Duration of treatment, an average of 3 to 4 weeks. In a relapse refresher course with a time 2 months.
     When complications Leishmaniases secondary bacterial infection appoint a sulfanilamidnie antibiotics or drugs.
     Contraindications : an acute infectious disease associated with significant dystrophy and intoxication due to chronic illness, severe destruction of property not related to leishmaniasis.
     Note. In visceral leishmaniasis also proposed other schemes of solyusurmina. In visceral McLeish manioze if drug designate of the Life show-ing advice, do not.
     Product type : 20% solution in 10 mL ampoules.
     Storage : List B. In the dark place at room temperature.

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