SARGRAMOSTIM (Sargramostim).

     Synonyms : Leikin, Prokin, Leukine, Prokine.

     Glikolizirovanny polypeptide containing 127 amino acid residues. Molecular mass 15,500 -19,500 Dalton. (C639H1002N168O198S8).

     Getting through genetically engineering yeast Saccharomyces cerevisiae fungus.

     Promoting education granulotsitov, makrofogav and Eosinophils.

     Enter intravenous (infuzionno-within 2 h) or subcutaneously.

     Dose set individually.

     Typically used (with neutropenia associated with malignant tumor cytotoxic chemotherapy and transplantation of bone marrow) at the rate of 250 µ g of 1 m2 of body surface per day. If necessary, increase the dose to 500 µ g / m 2 per day.

     In applying the drug may breach vascular permeability, the delay fluid in the body, difficulty in breathing, weakness, fever, trombophlebitis, brain.

     Product : powder for injection solutions in bottles of 0.25 and 0.5 mg.

     The contents of a bottle dissolve in 1 ml of sterile water for injection (not vstryahivaya- to avoid foam). For infusions grow again in 0.9% sodium chloride solution.

     Storage : with a temperature of 2 to 8 ° C.

Materials allowed to copy only with the active hyperlink to the handbook of medicines