SALAZODIMETOKSIN (Salazodimethoxinum). 5 - (para-[(2, 4, 6 Dimetoksipirimidinil-) - sulfamido] - fenilazo) - salicylic acid.

     Burovato- orange melkokristallichesky odourless powder. Almost nerastvorim in water, very little is soluble in alcohol, slightly caustic soda in solution.

     Like salazosulfapiridinu and salazopiridazinu drug dissolves in the gut, with the formation of 5-aminosalicylic acid and sulfadimetoksin providing antiinflammatory and antibacterial action. Diluted malotoksichen. A smaller doses than salazosulfapiridazin.

     For the operation and the use of testimony similar to salazopiridazinom and salazosulfapiridinom.

     Assign inside (after eating) about the same doses, and at the same time as salazopiridazin. 0 t give adults : 0.5 to 4 grams per day (1 g or two times a day) for 3 to 4 weeks, and then (during this period due therapeutic effect) of 0.5 g 2 - 3 times a day in the next 2 to 3 weeks. In severe forms of the disease increases daily dose in the early days to 4 g, and after declining frequency chairs, reduce dose. In milder forms of the disease can begin with one dose, 5 grams a day, in the absence of effects go to 2 g per day.

     Children aged 3 to 5 years in the first 7 to 14 days to designate 0.5 grams a day, in the next two weeks-to 0.25 g / day in the remaining days (40-50 day from the start of treatment ) to 0,125 g / day; children between 5 and 7 years, respectively, for 0.8-1, 0 g; 0,4 - 0,5 - 0,2 g and 0.25 g; from 7 to 15 years - 1, 0-1, 5 g; 0.5 - 0.75 g and 0.25 -0.375 city diem doses given in 2 - 3 admission.

     If in the first 14 days of the start of treatment fails to obtain therapeutic effect, salazodimetoksin cancel, you have to use salazopiridazina or salazosulfapiridina (sulfasalazina).

     To prevent a recurrence of non-ulcerative colitis and Crohn disease, salazodimetoksin appointed permanently to gradually reduce the dose : 0.5 grams for adults 1 to 2 times a day every day for 2-6 months, then 0.25 - 0.5 g daily or a day for 6 to 12 months. Children drug designate smaller doses for age and dose used in the acute period of disease. In the case of deterioration of the dose salazodimetoksina increase.

     Possible side effects and contraindications such as using salazapiridazina.

     Product : 0.5 grams of pills in a package of 50 and 100 pieces.

     Storage : List B. In the dark spot.

Materials allowed to copy only with the active hyperlink to the handbook of medicines