RISPERIDON (Risperidone).

     3-[2-[4 - (6-Fluorine-1, 2-benzoksazol-3- mud) piperidino] ethyl] tetragidro-2- 6,7,8,9-methyl-4 H-pirido [1,2 - a] pirimidin-1- it.

     Synonyms : Rispolept, Rispolept, Risperdal.

     Belovato- beige powder. Almost nerastvorim water, easily soluble in methylene chloride and methanol.

     Is blokatorom selective serotonin 5-NT2-, D2- dofamine, A-adrenoreceptor and N1- gistaminovyh receptors.

     Quickly and completely absorbed in the digestive tract, A max is 1-2 h, T1 / 2 risperidona and its active oksimetabolita-3 and 24 h; Displayed in the kidneys.

     Applied with schizophrenia and other psychoses-dominated productive disorders (delirium, hallucinations) and negative symptoms as well as vegetative disorders in patients with schizophrenia.

     Assign the inside, starting with 0,001 g (1 mg) two times a day and increasing daily dose of 0,001 g to achieve therapeutic effect. Average daily intake 0,004-0,006 grams (4-6 mg). Older patients with kidney and liver failure designate 0.0005 g (0.5 mg) two times a day. The maximum daily dose of 0,004 grams (4 mg).

     In applying risperidona possible sleep disorders, increased anxiety, extrapiramidale disorders, diarrhoeal phenomenon, arterial hypotension, tachycardia, Galactorrhea, Bitch.

     Decreases effect of levodopa.

     Be wary designate patients with cardiovascular diseases, including heart attack in history, stroke and epilepsy, Parkinson's disease. In developing the neuroleptic malignant syndrome (hyperthermia, muscle rigidity, violation of consciousness) product overturned.

     Method of issuance : pills to 0,001; 0,002; 0,003 and 0,004 grams (1; 2; 3 and 4 mg) (N. 10, 20, 60); 0.1% solution for admission into the interior bottles of 30 and 100 ml.

     Storage : List B.

Materials allowed to copy only with the active hyperlink to the handbook of medicines