Riboflavin- mononukleotid (riboflavinum-mononucleotidum)


RIBOFLAVIN- MONONUKLEOTID (Riboflavinum-mononucleotidum). 7, 8 Dimetil-10- (1-D- ribitil) - izoalloksazin-5'- sodium phosphate or sodium riboflavin-5'- monofosfat.
     Synonyms : Riboflavinfosfat, Flavin- mononukleotid, Alloxazinmo-nonucleotid, Coflavinasi, Cytoflav, Flamotide, Ribofosfina and others.
     Crystal orange-yellow powder odourless, bitter taste. It is soluble in water; Almost nerastvorim of alcohol. In light degrades. Aqueous solutions (pH 5, 5, 6, 5) are zheltovatooranzhevy color, intensely flyuorestsiruyut in ultra-violet light.
     Riboflavin- mononukleotid like kokarboksilaze, approaching on the biological effects of vitamins and enzymes. A product PHOSPHORYLATION riboflavin, riboflanin- mononukleotid is finished form kofermenta formed in the body of riboflavin. In connection with protein riboflavin- mononukleatid member of the enzymes regulating the redox processes (yellow and oxidative enzyme tsitohromreduktaza); Also participating in the processes of protein and fat exchange; Playing an important role in the maintenance of visual function eye.
     Applied riboflavin- mononukleotid as medicine with beri - beri gipoi 2 (ariboflavinoze); When zudyaschih Medicine, chronic eczema, neyrodermitah; Fotodermatozah and other skin diseases; When keratitis, conjunctivitis, corneal thickness and as a means of generally strengthening the power of the violations; When neurasthenia , and other diseases. The good solubility in water (unlike riboflavin) allows riboflavin- mononukleotid parenteral (intramuscularly and subcutaneously).
     Enter riboflavin- mononukleotid intramuscularly (or skin) for adults to 0.01 g (1 ml of 1% solution) 1 per day; Treatment 10 - 15 - 20 days. Children appoint 0,005 - 0,01 g (0.5 to 1 ml 1% solution) during the first 3 to 5 days, then 2 to 3 times a week.
     In ophthalmology at chasheobraznyh cataract using 1% solution riboflavin- mononukleotida for instillyatsy in konyunktivalny bag.
     The drug is usually well. Several painful injections.
     Product : 1% solution in 1 ml ampoules.
     Storage : in the dark spot.
     Rp. : Sol. Riboflavini-mononucleotidi 1% 1 ml
     D.t.d. N.15 in a mpull.
     S. On January 1 ml once a day intramuscularly
     Riboflavin- mononukleotid member of the integrated (polivitaminnogo) product "Komplivit."

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