Reopoliglyukin (rheopolyglucinum)


REOPOLIGLYUKIN (Rheopolyglucinum). 10% solution of glucose-polymer dextran (see Poliglyukin) with relative molecular mass of 30000 - 40000 with the addition of isotonic sodium chloride solution.
     The transparent colorless or slightly yellowish liquid. Relative strength at temperatures + 25 'C, a maximum of 5, 5.
     Reopoliglyukin a drug nizkomolekulyarnogo adextran. It reduces the aggregation of standard elements of blood, contributes to the displacement of the tissue fluid in the blood track. Therefore, the preparation improves suspension characteristics blood reduces its viscosity to help restore blood flow in small capillaries, has dezintoksikatsionnoe effects, cautions and reduces aggregation of blood formed.
     Reopoliglyukin as poliglyukin, flushed from the body in the kidneys, with the first day in output about 70%.
     When applied violations kappilyarnogo blood, for the prevention and treatment of traumatic, operating shock and burns; Violations of arterial and venous blood; For the treatment and prevention of thrombosis and tromboflebitov, endarteriita; Operations at the heart of using artificial circulatory system (for addition to applying liquid ); in vascular and plastic surgery to improve local circulation; for detoxification with burns, peritonitis, pancreatitis, etc.
     Reopoliglyukin appointed in retinal diseases and visual nerve (complicated myopia, retinal dystrophy and others), inflammatory processes cornea and vascular skin.
     With the aim of preventing and treatment of capillary blood flow associated with trauma, shock operating and Burns, using intravenous drip 400-1000 ml (up to 1500 ml) reopoliglyukina (within 30 min 60). When operational intervention in the heart and vessels to enter operation intravenous drip for 10 ml / kg, during the operation 400-500 ml for 5 to 6 days after the operation and 10 ml / kg for the introduction.
     In operations using artificial circulatory system reopoliglyukin added to the blood at the rate of 10 to 20 ml / kg. For detoxification injected drip 400-1000 ml. If necessary, you can on the same day a further 400-500 ml, and for the next 5 days to introduce 400 ml per day (drip).
     Children with various forms of shock, imposed on May 10 ml / kg (up to 15 ml / kg) in cardiovascular operations are children under the age of 2 to 3 years to 10 ml / kg one time a day (within 60 min) , to 8 years and 7 to 10 ml / kg (1 2 times daily), to 13 years in the 5 to 7 ml / kg (1 to 2 times daily), over 14 years - dose for adults. For detoxification impose a 5 - 10 ml / kg for 60-90 minutes.
     A dehydrated patients appropriate to add reopoliglyukinu isotonic sodium chloride solution, or 5% glucose.
     With reduced kidney filtering abilities or limitations need a sodium chloride, appoint reopoliglyukin with glucose (see).
     Complications after reopoliglyukina usually not observed. There are, however, allergic reactions; In those cases, impose solution of calcium chloride, glucose, protivogistaminnye drugs, heart funds.
     The drug is not suitable for thrombocytopenia, kidney disease (with anuriey), heart failure and where there should be large quantities of fluid.
     In ophthalmic practice reopoliglyukin used by electrophoresis. The procedure to 1 every day. Applied to 10 ml (with positive or negative pole; Current densities of 1, 5 mA / cm 2).
     The process 15 - 20 min (in the course of 5-16).
     Electrophoresis is contraindicated in enfleurage skin century, the abundant slizistognoynom separated.
     Product : in the hermetically ukuporennyh bottles, 100; 200, and 400 ml.
     Storage : at a temperature of 10 + to 25 + 'C.

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