RALTITREKSID (Raltitrexed).

     N-[5-[[(3-methyl Digidro-2- okso-6- hinazolinil) - methyl] metilamino] -2 - tenoil] -L- glyutaminovaya acid.

     Synonym : Tomudeks, Tomudex.

     Cytostatic substance timidilatsintetazu inhibition and DNA biosynthesis.

     Applied with large bowel cancer, pancreatic, and breast.

     Assign intravenously for 2,5-3 mg / m 2 1 every 3 weeks (T? At 168 h), if necessary, re-enter.

     Possible side effects : violation of taste, anorexia, diarrhoeal phenomenon radiation, thrombocytopenia (rarely), anemia, fatigue, convulsions, peripheral oedema, Alopecia, sweating, rash.

     Contraindications : mielosupressiya expressed violations kidney functions, pregnancy, breast-feeding.

     It should not be used in conjunction with folic acid.

     Product : dried powder for injection solutions in vials of 0,002 grams (2 mg).

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