PROTIONAMID (Protionamidum).

     Tioamid a-propilizonikotinovoy êè c lots, or two-tiokarbbamoil-4- tsiridin sold.

     Synonyms : Treventiks, Prothionamide, Protionamide, TN 1321, Teraplix, Treventix, Trevintix.

     Chemically similar to ciprofloxacin, is only a substitute for radical ethyl (C 2 H 5) 2 in a position to propilny (Sz H).

     For TB activity does not differ significantly from ciprofloxacin, but better postponed.

     It may be used in combination with isoniazid, pyrazinamide, tsikloserinom and other anti-TB drugs.

     The drug is recommended bad perenosnmosti ciprofloxacin, but because of the cross-sustainability, it should not be appointed to develop Mycobacteria tuberculosis resistance to ciprofloxacin.

     Is inside after eating. Adults are 3 to 0.25 grams per day; With good endurance for the 0.5 g 2 times a day (1 g / day). Patients who are over 60 years of age and birth weight of less than 50 kg, the daily dose should not exceed 0.75 (mostly on the 0.25 g 2 times daily). Children are designated at the rate of 10-20 mg / kg per day.

     In applying the drug can gastrointestinal disorders, skin reactions, dizziness, tachycardia, weakness, parestezii, but expressed less side effects than in the application of ciprofloxacin.

     The drug should not be appointed in pregnancy.

     Product : pills (pills) to 0.25 g.

     Storage : List B.

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