PROPANIDID (Propanididum).

     PROPYL West methyl ester (N, N-dietilkarbamoilmetoksi) - feniluksusnoy acid.

     Synonyms: Sombrevin, Epontol, Fabantol, Fabontal, Propanidid, Propantan, Sombrevin.

     Light yellow oily liquid light. Nerastvorim water. To use a special detergent solution (surface-active substance).

     Propanidid-vehicle intravenous anaesthesia discharged action. Drug effect after intravenous developed through 20-40 S. Surgical stage anaesthesia continues 3 to 5 minutes. Anaesthesia is without initiation stage. Consciousness is restored after 2 - 3 min after the end of surgery under anaesthesia; After 20 to 30 minutes of the drug being fully.

     Apply for a short introductory and anaesthesia. The product is easy to use, with short-term operations in outpatients and diagnostic studies (biopsies, lumbar vyvihov, repozitsiya otlomkov bones, taking beads, catheterization, bronchoscopy and bronchography, removal of the teeth, etc.).

     Enter the drug intravenously (slowly), usually in the same syringe with a 10 cent solution of calcium chloride, the average dose of 5-10 mg / kg. Weakened sick and elderly people entering 3 - 4 mg / kg adult, in the form of 5% solution, and exhausted elderly patients, as well as children, in the form of 2.5% solution.

     The extension can be repeated injections of the drug (1 to 2 times); With repeated injections dose reduce to 2 / 3 to 3 / 4 of the original.

     Separate data and application sombrevina water anaesthesia for Caesarean section in the dose of 10 to 12 mg / kg while inhalation of nitrous oxide and oxygen (1:1 or 2:1). Principal anaesthesia to a mixture of nitrous oxide with oxygen.

     Using propanidida hyperventilation may occur with subsequent oppression of breath, tachycardia, nausea, Hiccup, the muscle car, sweatiness and blood during the vein.

     Propanidid metabolized in the liver. Products metabolism are kidneys.

     The product contraindications to choke, defeat liver, kidney failure. Caution is needed for violations of coronary circulation, heart activity dekompenstsatsii expressed hypertension.

     With great care and strict individually apply Propanidid children under the age of 4 years and among persons over 60 years of circulatory failure or hypertension.

     Form release: 5% solution in the ampoule and 10 ml (1 ml of a 50 mg product), in a package of 5 and 10 vials.

     Storage: List B.

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