PROPAFENON (Propafenone) *. 2'- [2-Gidroksi-3 (propilamino) propoksi] -3-phenyl propiofenon.

     Available as hydrochloride.

     Synonyms : Prolekofen, Fenopraine, Norfenon, Normoritmin, Prolekofen, Ritmonorm, Rythmonorm.

     Has antiaritmicheskoe and koronarorasshiryayuschee effect. Refers to antiaritmikam Group I : lengthens refrakterny same period predserdy and ludochkov, raised the threshold of excitability, hampering education institution and its spread from predserdy to Poly.

     Effective with various violations of heart rhythm. Is applied to the treatment of edema and zheludochkovyh and nadzheludochkovyh ekstrasistoly when syndrome Wolff - Parkinson-White.

     Applied intravenously and inside. In the vein type usually dose to 1 mg / kg (of O 2 to 5 mg / kg), slow-within 3 to 6 minutes by EKG.

     The interval between the first and second injection should be 90, 120 min.

     When adults impose heavy drip in isotonic (5%) solution glyu goats. Infusion beginning after 3 to 5 min after intravenous bolyusnogo. Supporting - dose 0.3 mg / kg per hour.

     Inside designate dose of 0.6 g (600 mg) a day (four times for 150 mg or 2 x 300 mg), sometimes up to 0.9 grams per day.

     Possible side effects, precautions and contraindications are the same as for other complications drugs group I (for the excluded asset side effects antiholinergicheskoy nature inherent dizo pyramid).

     Method of issuance : in 20 ml ampoules containing 70 mg propafenona and 10 ml containing 35 mg; Tablets of 0.15 and 0.3 g (150 and 300 mg).

     Storage : capsules, with a temperature of 15 to 25 'C (not less than 15' C), pill-dry, the dark place at a temperature of not more than 25 'C.

Materials allowed to copy only with the active hyperlink to the handbook of medicines