PROLONGIROVANNYE MEDICINAL TEOFILLINA forms.

     Theophylline is a key component eufillina (see), a member of the combined some tablets teofedrina-N (see below) and containing 0.25 tons and 0,025 grams teofillina dimedrol. Sometimes prepare ex tempore combination with teofillina dimedrol, ephedrine, and other inflammatory drugs. Recently, Theophylline have combined with modern bronhorasshiryayuschimi drugs. Thus, in one pill drug "Teo- Asthalin (Theo-Asthalin) contains 0.1 grams and 0,002 grams teofillina one (see).

     Teofedrin N (Theophedrinum N). Tablets containing teofillina 0.1 g, 0.05 g of caffeine, paracetamol 0.2 grams of phenobarbital and ephedrine to 0.02 g, 0,003 g herb extract, tsitizina 0.0001 g.

     Applied as a treatment and preventative tool in bronchial asthma.

     Adults appoint 1/2-1 pill (with strong attacks two tablets) one time (and, if necessary 2 - 3 times) per day, children 2-5 years in the 1/4- 1 / 2 pills, 6-12 years on 1/2-3/4 pills. In order to sleep at night teofedrin should take the morning or afternoon.

     Contraindications : glaucoma, a violation of coronary circulation, Ray.

     STORAGE : List B.

     Note. 1. Previously issued Teofedrin pills "contain" instead of paracetamol Phenacetin. In connection with the exception of medicines fenatsetina Nomenclature (because of side effects) created Teofedrin "N" (new), which replaced Phenacetin paracetamol. This therapeutic effect (bronholipmeskoe) survived.

     2. In terms of composition and actions "Teofedrin" close to the foreign drug "Antastman (Antasthman) does not have now widely adopted.

     Teopek (Theopecum). Tablets containing at 0.1; 0.2 and 0.3 g teofillina combined with composite polymer carrier.

     Domestic drug teofillina prolonged action. Has specific pharmacological properties teofillina, but the combination of composite polymer carrier to release teofillina measured in blood : C max seen through 3-6 h after administration of tablets inside, and the total duration of drug detection in plasma reaches 12-24 h.

     Assign an adult in as a bronchodilator in the various forms of bronchospasm : in bronchial asthma, chronic bronchitis obotruktivnom, pulmonary emphysema and other light

     Is inside (after eating), squeezed water. Pill can be done in half, but could not pulverize (tooth) and dissolving in the water. During the first 1-2 days of preparation appoint 0.15 g 1-2 times a day at intervals of 12-24 h, the subsequent growth of a single dose of 0.3 g 2 times a day.

    Optimal dose and duration of use teopeka set individually, taking into account the clinical, patient weight, endurance drug related diseases, while others receive LS. To that end, in the treatment process to determine the desirable teofillina content in the blood. Tentatively its therapeutic concentration in plasma must be 10-15 ug / ml. Duration of treatment 2 to 3 months or more.

     In applying teopeka possible dizziness, headache, tachycardia, anxious, sleeping, anorexia, nausea, vomiting, pain in the stomach. In these cases, reduce the dose or stop medication. The development of side effects are more likely to coronary insufficiency, inclinations to tachycardia, epileptic fits, chronic gastritis, colitis, liver failure.

     Indications are the same as those teofillina.

     STORAGE : List B.

     Teobiolog (Theobiolongum). Pills containing 0.1 grams of teofillina with biorastvorimym polymer used for eye films (see eye to pilokarpinom Films).

     Domestic drug prolonged action. Step teofillina continues through slow release when administered during 10-12 h.

Indications and contraindications, precautions such as a pill "Teopek" (see also Theophylline).

     Is inside after eating (not razmelchaya and dissolves in water), from 0.1 g (1 tablet) two times a day (morning and evening) with an interval of 12 h. In effect, and lack of good endurance gradually increase the dose to 0,2-0,3 g per reception. Under the dose should not exceed 0.3 grams per day increase was 0,6-daily dose (more than 0.3 grams), only in rare cases under strict medical supervision.

     As the operation was not substantially different from teopeka, which is slightly more long-term. Before teobiolonga increasingly seen tachycardia, headaches.

     STORAGE : List B.

     Abroad, under the title "Afonilum SR (Afonylum SR)," Spofillin retard "(Spophylline retard)," Teodur (Theodur), "Teotard (Theotard) Durofillin" retard "(Durophyllin retard)," Retafil (Retaphyl ), «Âåíòàêñ» (Ventax) è äðóãèìè âûïóñêàåòñÿ ðÿä ëåêàðñòâåííûõ ôîðì òåîôèëëèíà ïðîëîíãèðîâàííîãî äåéñòâèÿ â âèäå òàáëåòîê èëè êàïñóë ñ ãðàíóëàìè (ñîäåðæàò îò 0,1 äî 0,375 ã òåîôèëëèíà), èìåþùèõ ïðåèìóùåñòâî ïåðåä òåîôèëëèíîì. Slow release teofillina of them offers (when administered), his uniform blood flow in the current, slow-growing concentration in plasma and the effect of a longer (up to 12 hours and longer), better portability. In connection with the prolonged effect an important indication for the use of night-warning and pre-event bronchospasm.

     Assign 1-2 times a day.

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