Prolonged dosage forms quinidine


PROLONGIROVANNYE MEDICINAL HINIDINA forms.
     Recently, in order to slow intake quinidine, in the maintenance of blood and tissue concentrations uniform and reduce side effects, but also to be able to increase the interval between drug receptions established prolonged dosage forms quinidine.
     The most popular foreign drug "Hinidin- unique forests." There is also domestic product "Hinipek."
     Hinidin- durules (Chinidin-durules) *. Consists of insoluble Poris of the foundation, which is located in the pores bisulfat quinidine. One tablet contains 0.25 g quinidine bisulfate, which corresponds to 0.2 g quinidine sulfate. Bisulfat apply because it will be soluble in water and evenly allocated polymer base.
     After receiving the maximum drug concentration in serum skills normally achieved through 3-6 h and then slowly decline. To maintain therapeutic concentration sufficiently 2 to 3 times a day to take pills.
     Indications and contraindications are the same as for quinidine.
     Before systematically take pills, worth checking portability, taking one pill conventional quinidine or quinidine durulesa. In the future, appoint one-two-three tablets three times a day; The optimal dose picked individually depending on the efficiency and portability.
     Pills proglatyvayut not liquid and not rassasyvaya.
     Similar drugs are produced abroad under the title "Kinilen dead (" K inilentin ")," Kiniduron (K iniduron ").
     Pills "Hinipek, coated (Ta buletta e" Chiniprec "obductae 0.2). Patriotic prolonged drug quinidine.
     Pill-coated white with a yellowish sheen color, containing 0.2 g quinidine sulfate, polymeric media and by the Sub substance.
     The drug has prolonged antiaritmicheskoe effect. After receiving a single concentration in the blood is stored in a 10 - 12 h.
     Therapeutic effect is usually 1 - 2-day, and persistent treatment effect on the third day of the start of the reception.
     Indications and contraindications are the same as for quinidine.
     Assign an adult for 30 minutes before eating. Pills should swallow, not liquid and not rassasyvaya.
     Prior to the systematic treatment check portability, taking one pill normal quinidine or hinipeka.
     Dose picked individually, at an average rate of 1 to 2 grams per day.
     Assign 2 times a day at intervals of 12 hours Initial doses typically 1, 2 g / day (2 to 3 tablets twice a day), supporting and preventive 0.4 - 0.8 g / day (1 - 2 2 pills twice a day).
     If necessary daily dose can be increased to 2, 4 g.
     Product : tablets in a package of 50 pieces.
     Storage : List B. In the dark spot.

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