PRODIGIOZAN (Prodigiosanum).

     Vysokopolimerny lipopolisaharidny compound isolated from a microorganism you. p rodigiosum.

     Amorphous powder or porous mass of white with yellow amber shade of the color, no smell and taste. It is soluble in water, virtually nerastvorim of alcohol; Divorced soluble in mineral and organic acid and alkali. Gigroskopichen.

     Refers to a group of bacterial polysaccharides. It is a means for encouraging factors, and non-specific resistance. Activates T immune system function and adrenal cortex.

     Step prodigiozana largely linked to the stimulation of endogenous immune systems of the body, activate interferon education (see Interferon), from interferonogennoy activity.

     Prodigiozan applied as a motivating tool in the treatment of various diseases with a reduction in the body's immune reactivity : chronic inflammatory processes in the aftercare period, the treatment of antibiotics (especially in the course of chronic illness), as weak healing wounds, radiation therapy and others.

     Prodigiozan not replace specific therapy, but in some cases increase its effectiveness.

     Applied in a sterile 0.005% solution for injection in isotonic sodium chloride solution with the addition of a buffer to pH 5, 7, 7, 0. Colorless, slightly opalestsiruyuschaya liquid.

     Enter intramuscularly. Dose set individually depending on the nature and severity of the disease, portable and cure.

     Tentatively set portability products, introducing 15 µ g intramuscularly to adults and children 10 ug drug.

     With good endurance, starting 3 days treatment. Regular single dose for adults is 25 -30 µ g (0.5 - 0.6 ml of 0.005% solution). Enter at intervals of 4 to 7 days. The course of treatment consists of 3-6 injections. Sometimes single dose increased to 50 and 100 µ g (maximum).

     Children are introducing lower drug doses (10 to 20 µ g).

     There are performance prodigiozana with infectious inflammatory diseases of the respiratory system in the form of aerosol inhalation. Assign an adult 4 - 5 inhalation of 5% solution of 0,005 ml (1 inhalation 2 times a week). Combined with the antimicrobial therapy received positive. Applied also inhalation prodigiozana children.

     Treatment prodigiozanom be conducted under close medical supervision. After 2 to 3 h after injection of some patients increased body temperature, appear headache, lomota in joints, general malaise.

     There radiation, smenyayuschayasya leucocytosis. These phenomena are usually 2 to 4 hours For patients with chronic ulcers in some cases had worsened disease, increasing abdominal pain, diarrhea appears.

     In inhalation may also increase body temperature, fever, pain in muscles. In subsequent inhalation these events usually take place.

     The drug is contraindicated in the central nervous system lesions, acute coronary insufficiency, heart attack,

     Product : 0,005% injection in 1 ml ampoules.

     Storage : in the dark place at a temperature of up to + 4 + 8 'C.

     R p. : Sol. R rodigiosani 0.005% 1 ml

     D.t.d. N. in ampull 6.

     S. For intramuscular injections (0.5 to 0.6 ml - 1 in every 4 to 7 days)

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