Pregnin (praegninum)


PREGNIN (Praegninum).
     Pregnen-4- in-20- 17 b-ul-on-3, or a 17-etiniltestosteron.
     Synonyms : Aethisteronum, Ethisterone, Ethisteronum, Gestone-Oral, Lutocycol, Nalutron, Oraluton, Pranone, Pregneninolone, Pregnoral, Progestoral, Proluton C et al.
     White or white with a yellowish sheen crystalline powder. Almost nerastvorim in water, very little is soluble in alcohol, soluble in oils.
     Pregnin is a synthetic hormone similar to the yellow body (progesterone). Biological and clinical effect similar to the natural hormone; He, however, is less active (5 to 6 times) than progesterone. Features pregnina compared with progesterone is the property remain active and have a therapeutic effect when administered or sublingvalno (blowing through the mucous membrane of the mouth).
     Pregnin as progesterone, appointed in violation of ovarian function, the lack of yellow body. In dysfunctional uterine krovotecheniyah and pregnin and progesterone appointed to lead the transition endometrium in the pre-condition that can lead to the cessation of bleeding. Pregnin apply also to amenorrhea, gipooligomenoree, algomenoree. For infertility pregnin (like progesterone) designate after oestrogen use drugs. In a familiar, threatening and starting miscarriage pregnin not apply.
     Assign usually 0,01 - 0,02 g (10-20 mg) 2 - 3 times a day in pill form under the language. With strong krovotecheniyah dose increased to 0.05 - 0.06 g / day and pregnin combine with androgenami.
     Higher doses for adults : single 0.02 grams daily 0.06 g.
     Pill pregnina to keep the language until the dissolution of that preparation was blowing through the mucous membrane of the mouth. This way of enhancing the therapeutic action than in the employment drug inside.
     Product : pills to 0.01 g.
     Storage : List B. In the dark spot.
     Rp. : Tab. Praegnini 0.01 N.20
     D.S. For tablets 3 times a day (by the language)

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