Podofillotoksin (podophyllotoxin)


PODOFILLOTOKSIN (Podophyllotoxin).
     (5R, 5aR, 8aR, 9R) -5,8,8 a 9-Tetragidro-9- oksi-5- (3,4,5 - trimetoksifenil) furo [3? , 4? : 6,7] naphtha [2 ,3-d] -1,3 - dioksol-6 (5 aN), he said.
     Synonyms: Kondilayn, Kondilin, Condilin.
     Active component podofillina isolated from plant extracts family Coniferae and Berberidacea. Soluble in alcohol, partly in the water.
     Provides cytostatics and nekrotiziruyuschee (local) effect.
     Apply local outer edge of genital kondilomah (men and women).
     Each kondilomu cause (through off) 0.5% solution of 2 times a day (morning and evening) during the three days each week. The average rate of 4 weeks.
     Possible side effects: local, redness, pain, itching, шелушение; System-nausea, dizziness, pitting mucous membranes.
     Contraindications: pregnancy, breast-feeding, child age.
     Form release: 0.5% solution for external use in vials of 3.5 ml.
     Based podofillina received polusinteticheskie glycosides etoposide and Teniposide, effective in certain types of tumors.

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