PITUITRIN FOR INJECTION (Pituitrinum pro injectionibus).

     Hormonal drugs obtained from the back of pituitary cattle and pigs.

     Has oksitotsicheskoy (breeding), and vazopressornoy antidiureticheskoy activity. As of close to the foreign drugs Glanduitrin, Hypophen, Hypophysin, Piton, Pituglandol, Pituigan and others.

     A transparent colorless liquid acid reaction (pH 3, 0, 4, 0). Canned 0.25 - 0.3% solution of phenol.

     The main active substances are pituitrina oxytocin and vasopressin (pitressin). The first is reducing the uterine musculature, the second narrow capillaries and the AD, is involved in regulation of osmotic pressure permanence blood, causing an increase in water reabsorbtsii izvityh Channel kidney and reducing reabsorbtsii chlorides.

     Activity pituitrina standardizes biological methods; 1 ml of the drug must contain 5 ED.

     Apply for initiating and enhancing sokratitelnoy of the uterus in primary and secondary her weaknesses and perenashivanii pregnancy; Gipotonicheskih krovotecheniyah early postpartum period; To normalize involyutsii uterus in the post and posleabortnom periods.

     The product introduced under the skin or intramuscularly for 0.2 - 0.25 ml (1, 0, 1, 25 ED) every 15 - 30 minutes 4 to 6 times. To enhance the effect can be combined with pituitrin vnutrimyshechnym of estrogen (see Follikulin).

     Pituitrina single dose of 0.5 to 1, 0 ml (2, 5, 5 ED) can be used in the second period births in the absence of obstacles to move the ball quickly and fruit delivery.

     To prevent and stop bleeding gipotonicheskih early postpartum period pituitrin impose sometimes intravenously kapelno [1 ml (5 ED) in 500 mL of 5% glucose solution] or very slowly (0.5 to 1 ml in 40 ml of 40% glucose solution).

     In connection with the preparation of antidiureticheskim applied to incontinence of urine at night and nesaharnom diabetes (see Adiurekrin) Enter under the skin and muscles in adults and 1 ml (5 ED), children under 1 year of 0.1 - 0.15 ml, 2 to 5 year-on 0,2 - 0,4 ml; 6-12 years - 0.4 0.6 ml of 1 - 2 times a day.

     Higher doses for adults: an ED 10, daily 20 ED.

     Contraindications: pronounced atherosclerosis, myocarditis, hypertension, physiotherapists, sepsis, nephropathy pregnant. The product is not appoint if scarring of the uterus, uterine cancer risk gap, the wrong situation fruit.

     Large doses pituitrina, especially with his quick introduction, can cause brain vascular spasm, violations hemodynamics, collapse.

     Form release: in ampulyah 1 ml containing 5 ED.

     Storage: List B. In sheltered from the world scene with a temperature of +1  to +10  C.

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