Pindolol (pindololum)
PINDOLOL (Pindololum) *. 1-(4-Indoliloksi) -3 - izopropilamino-2- propanol.
Synonyms : Wisken, Betadren, Blocklin, Carvisken, Durapindol, Pectobloc, Pinadol, Pinbetol, Pindomex, Pinloc, Prindolol, Viscen and others.
Is nekardioselektivnym b-adrenoblokatorom. Has internal simpatomimeticheskoy activity. As of close to oksprenololu (trazikoru). Has antianginalnoe antiaritmicheskoe and anti-hypertensive effects. On intensity of the few losing prophylaxis (anaprilinu).
As antiaritmicheskoe means : particularly effective in predserdnyh ekstrasistoliyah; Also used for cupping the zheludochkovyh arrhythmia (intravenous).
Assign inside and parenteral.
As antianginalnogo antiaritmicheskogo funds and designate the interior of 0,005 grams (5 mg) three times a day; In more severe cases, and 10 mg three times a day. Is inside 30 minutes after eating.
In hypertensive disease (see Anaprilin) designate, starting with the 5 mg 2 - 3 times a day; If necessary, gradually increase the dose to 45 mg a day (3 admission). Anti-hypertensive effect is less pronounced than in the application anaprilina. You can combine the application pindolola with fat retikami antigipertenzivnymi and other drugs (in small doses).
Enter intravenous slowly (over 5 minutes), 0.4 mg (2 ml of 0.02% races creators) and AD controlled pulse. You can re-enter at 1 mL (0.2 mg) in 15 - 20 minutes. There effective drug in the PNDS crises in patients with hypertensive disease stage I and II (1 mg introducing 20 ml 5% glucose solution).
Possible side effects and contraindications are the same as in other indiscriminate in the smallest b-adrenoblokatorov (see Anaprilin).
Method of production : tablets of 5, 10 and 15 mg; Pill may require slow to 20 mg; Solution for admission into the content of 5 mg in 1 ml (0.5%) - 20 drops in 1 ml; 0.004% solution for injection of ampoules and 2 ml (0.4 mg in the ampoule).
The so-called "Viskaldiks (Viskaldix) issued pill, helping shares : 10 mg and 5 mg pindolola diureticheskogo drug klopamida (see). Used to treat hypertension.
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