FTORAFUR (Phthorafurum).

     III (2-Four a nidil-5- ftoruratsil).

     Synonyms: Citofur, Fluorofur, Ftoral, Furafluor, Futraful, Lamar, Lifril, Lunacin, Sinoflurol, Sunfular, Tegafur, Torafurine, Utefos and others.

     The white crystalline powder and odourless. It soluble in water and alcohol. Rastvorima sodium salt in the water; Flint appears as a transparent solution.

     Ftorafur is derived isomers (prolekarstvom). Antitumor effects due ftoruratsilom released in the body. Compared with ftoruratsilom, ftorafur better transferred patients. At the blood is like ftoruratsilu, leading to a high dose radiation, thrombocytopenia and anemia.

     When you receive inside ftorafur rapidly absorbed.

     Ftorafur as capsules for the reception inside and sodium salt solutions for intravenous apply with malignant stomach tumor, thick, sigmovidnoy and rectum, breast cancer; When skin lymphoma (retikuleze skin), and diffuse neyrodermitah and endogenous uveitah.

     Enter sodium salt solution intravenously each day 1 to 2 times a day with an interval between the introduction of 12 hours Daily dose is usually 30 mg / kg, but not more than 2 grams total dose of treatment 30-40

     Inside appoint ftorafur capsules. Daily dose of 1, 6, 2, 0 g (30 mg / kg) in 2 admission to the interval 12 hours Dose for treatment of 40 - 60, if necessary through a 1 5-2 months repeat courses.

     When skin and lymphoma neyrodermite impose ftorafur intravenously to 0.4 g (10 mL of 4% solution) 1 every day. The course of treatment 10 to 15 introductions (total of 4 to 6 g product).

     When endogenous uveitah applied 4% solution method fonoforeza (vannochkovogo). The course of treatment 10 to 15 daily procedures to 5 minutes. Treatment for 2 - 3 times a year.

     In a lengthy application ftorafura and its sodium salt, and with high sensitivity patient may arise nausea, vomiting, stomatitis, diarrhoea, radiation, thrombocytopenia. Treatment should be under the control of blood (see Ftoruratsil).

     Violations of blood, vlivayut 100-125 ml of blood 2 to 3 times a week.

     With the introduction of intravenous drug may dizziness. To avoid this, it is recommended to inject ftorafura situation with the patient lying down.

     The product contraindications when blood levels below 3 x 10 9 / L and platelets less than 100 x 10 9 / L, in the terminal stages of illness, with liver and kidney disease, and acute profuznyh krovotecheniyah sharply expressed anemia.

     The use of drugs may be no earlier than one month after the previous radiation or chemotherapeutic treatment.

     Application ftorafura method fonoforeza counter with hypotension eye implicated retina and diseases in which excludes ultrasound treatment.

     Method of issuance: 4% solution of sodium salt in the ampoule and 10 ml (0.4 g in vials); HGC capsules, containing 0.4 g ftorafura, in a package of 100 capsules.

     Storage: List A. sheltered from the world scene.

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