Ftazin (phthazinum)


FTAZIN (Phthazinum). Metoksi-6- 3-(N-4 ftalilsulfanilamido) - piridazin.
     White or white with a slightly yellowish tinge crystalline powder odourless. Almost nerastvorim in water and alcohol. Easy soluble in alkaline solution and sodium bicarbonate.
     On chemical structure ftazin close, on the one hand, to ftalazolu, on the other, to sulfapiridazinu on antibacterial spectrum to sulfapiridazinu. In the slow defined free sulfapiridazina and long persistence of high concentration sulfapiridazina in the intestine, the drug is effective in treating intestinal infections.
     Ftazin better than ftalazol, absorbed from the bowel and has not only act in the intestine, but the total-rezorbtivnoe effect. In the blood of patients receiving ftazin, there are large concentrations sulfapiridazina that it is important to severe forms of dysentery, accompanied the body of intoxication.
     Ftazin apply in the treatment of dysentery, enterokolitov, colitis.
     Adults in one day appoint 1 g 1 to 2 times a day, in the next few days - to 0.5 grams per reception 2 times a day. In severe forms of dysentery appointed in Day 1 of 1 g 3 times in the following days, and 1 g 2 times a day. Children dose reduced in accordance with age. The course of treatment is continuing 5-7 days, if necessary, repeat the treatment after 4 to 5 days.
     Ftazin, as ftalazol sulgin and, if necessary, appoint conjunction with antibiotics.
     During the treatment given plenty of water.
     Ftazin generally well tolerated by. In some cases, side effects can be observed (diarrhoeic phenomenon, skin rashes, etc.); When expressed adverse drug events repeal.
     The product contraindications when the history of allergic reactions expressed MEPhI admission sulfanilamidnyh drugs.
     Method of issuance: powder; Tablets of 0.5 g.
     Storage: List B. In sheltered from the world scene.

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