Fepromaron (phepromaronum)


FEPROMARON (Phepromaronum). 3-a-b-Fenil- propioniletil-4- oksikumarin.
     White or white with a slightly kremovatym white crystalline powder and odourless. Almost nerastvorim in water, soluble in alcohol little.
     Like neodikumarinu is derived 4-oksikumarina but with a 4-oksikumarinovuyu group.
     By arrangement also applies to the action of vitamin K. antagonists Narushaet synthesis protrombina, prokonvertina, factor IX and X.
     Fepromaron has long antikoagulyantnoe effect. It has a cumulative effect. It is more active than neodikumarin, and appointed a lesser doses.
     Indications for use, contraindications and precautions are the same as for neodikumarina.
     Assign product inside. Doses choose individually. Initial dose is 0.5 mg per 1 kg of body mass patient, ie 30-50 mg (0,03 - 0,05 g).
     Supporting dose of 0,01 - 0,005 grams (10 - 5 mg) a day or every other day; Depending on the content in the blood protrombina supporting dose can be increased or decreased.
     Form release: pills to 0.01 grams in a package of 20 pieces.
     Storage: List A. sheltered from the world scene.

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