FENOKSIMETILPENITSILLIN (Phenoxymethylpenicillinum).

     Synonyms: Vegatsillin, Penitsillin- FAA, Apopen, Ascillin, Bramcillin, Distacillin, Faucilline, Fenoxypen, Meropenin, Oracilline, Oratren, Pencillin V Phenocillin, Stabicillin, Vaucillin, V-Cilin, Vegacillin and others.

     Dentists (fenoksimetilpenitsillinovaya acid) is an antibacterial substance; Produced talking Re nicillium notatum or various microorganisms.

     The white crystalline powder. Very little soluble in water. In January 1610 mg contains ED.

     On chemical structure differs from a dental group in the molecule fenoksimetilnoy instead benzilnoy; Different from dental acid, which makes it suitable for use inside. It breaks acid digestive juice; Well absorbed from the gastrointestinal tract and provides high and longer concentration of penicillin in the blood. Under the action penitsillinazy dentists destroyed.

     Primenayut dentists in the treatment of infectious diseases caused by micro-organisms sensitive to penicillin. Assign it mainly with moderately serious infection.

     The product is used in a preventive purpose in scarlet fever outbreak, with the flu, after tonzillektomy to prevent accidents attacks, as well as diphtheria carrier. When gonorrhea dentists less effective than drugs penicillin imposed parenteral transmission. For patients with syphilis (children and adults) use it if difficult to use drugs as penicillin injections, the drug in doses appointed inside than double dose parenteral penicillin in the introduction.

     Assign dentists inwards in the form of tablets or suspension. Take 1 / 2 to 1 hour before eating. The daily dose given at 4-6 receptions.

     The average single dose of 0.25 g for adults, daily-1, 5 grams or more. Children under 1 year of age shall designate in a daily dose of 25 to 30 mg / kg from 1 to 6 years old-15 - 30 mg / kg, from 6 to 12 years, 10 to 20 mg / kg over 12 - 0 on May 1, was 0

     Suspensions dentists appoint mainly children. Produce from the powder for suspension. In gm vial containing 1, 24 g of powder, add svezheprokipyachennuyu chilled water to the level of 100 ml; In vial with the contents of 0.62 or 0.31 grams of powder added water to 50 or 25 ml. The contents of the vial peremeshivayut to obtain uniform mist. In January mist contains 12 ml, 4 mg dentists (corresponding activity ED 2000). Doziruyut suspension specifically attached spoon (or tea spoon) or pipette with a capacity of 1 ml. One spoon (5 ml) contains almost 60 mg, and 1 ml of 12 mg drug. Best before finished suspensions (stored at a temperature of up to + 4 + 6 'S) not more than 14 days at room temperature no more than eight days.

     Duration of treatment dentists set individually depending on the nature of the disease.

     In severe forms of disease to start with vmutrimyshechnogo a dental appointment and then dentists inside.

     As benzylpenicillin, dentists may cause various side effects, including allergic reactions, disorders of the gastrointestinal tract (diarrhoea, vomiting) and others.

     P reparat contraindications to the high degree of sensitivity to penicillin. Do not appoint dentists in violation of aspiration from the gastrointestinal tract.

     Method of production: tablets of 0,1 and 0,25 g; Bean to 0.1 g; Powder preparation suspensions in vials containing 1, 2; 0.6 and 0.3 g dentists mixed with citric acid, sodium benzoatom, raspberry essence, sugar. Powder white, sweet taste, with the smell of raspberries. But filling in each bank (orange glass) is 80; 40 and 20 grams of powder.

     Storage: List B. In a dry, sheltered from the world scene at room temperature.

     Output abroad drug ospen (Ospen) [synonym: bimepen (imepen V)] is derived dentists (benzatin- dentists).

     Admission absorbed into slower than dentists, and provides a more uniform and prolonged retention of therapeutic concentrations in the blood.

     Issued in the form of tablets and syrup (ospen-750), designed primarily for use in paediatric practice. 5 ml of syrup (one measuring spoon) contains 750000 ED benzatin- dentists. Assign inside children aged 1 to 6 years, 2, 5 ml, 6 to 12 years and 5 ml, children over 12 and adults, and 10 ml three times a day.

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