PENTATSIN (Pentacinum).

     Trinatrievaya calcium salt dietilen- triaminopentauksusnoy acid.

     Synonyms : Calcii trinatrii pentetas, Calcium trisodium pentetate, Penthamil.

     The white crystalline powder. The easily soluble in water, virtually nerastvorim of alcohol. Aqueous solutions (pH 5% solution of 5, 5, 6, 8) are sterilized at a temperature of  + 100C for 30 minutes.

     Reservoir of complex compounds.

     Applied with acute and chronic poisoning plutonium, radioactive yttrium, strontium, zinc, lead and uranium mixture of products, as well as to identify those carrying radioisotopes. He has no significant impact on the development of uranium, polonium, radium and radioactive strontium and lead.

     The drug does not affect the content of krovn calcium and potassium.

     Applies intravenously in a 5% aqueous solution.

     Under the dose of 0.25 g of the drug (5 ml of 5% solution). In severe cases, a single dose can be increased to 1, 5 g (30 ml of 5% solution). Enter intravenous slowly, watching the state of the cardiovascular system. Injections produce 1 to 2 days; In the course of 10-20 injection.

     In a lengthy application pentatsina its effectiveness in removing radioactive isotopes drop After cessation of drug effectiveness is gradually recovering. Therefore, treatment for individual courses with a break between 3 to 4 months.

     In case of a crisis phenomena lead intoxication (lead colic) injected 1 - 2 g (20-40 ml 5% solution).

     To identify carrying radioactive isotopes and lead pentatsin appoint three consecutive days in dosage and research isotopes and lead content in the urine. Pre 3 days to control (background) study.

     In applying pentatsina sometimes possible dizziness, headaches, pains in the limbs and chest. These phenomena are usually alone. In case of nausea and vomiting reduce the dose or stop the use of drugs. In violation of coronary krovovbrascheniya drug overturned.

     When treating pentatsinom should be at least one per week to total urine, and identify diversion of urine radioactive isotopes. To avoid defeat kidney and electrolyte balance violations should comply breaks between courses injection drug.

     Pentatsin contraindicated in frenzied state, parenhimy kidney damage, hypertension violations kidney functions, as well as in patients with vascular spasm heart.

     Product : 5% solution of 5 ml ampoules in a package of 10 vials.

     Storage : Keep in a cool place protected from the light.

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