PANTOPRAZOL (Pantoprazole).

     5 - (Diftormetoksi) -2-[(3,4 - dimetoksi-2- piridinil) methyl] sulfinil] -1 H-benzimidazol.

     Synonym : Kontrolok, Controloc.

     Available in the form of sodium salt.

     White or almost white crystalline powder. Mg in the water.

     Perfect properties blokatora proton pump stomach with antimicrobial activity against Helicobacter pylori.

     Quickly and completely absorbed, bioavailability of 70-80%, S-max 2-4 h, T? 1-2 hrs; biotransformation are in the liver, kidneys predominantly displayed.

     Applied with stomach ulcers and gastrointestinal cancers (including refractor to medication N2- gistaminovyh receptor blockers), reflyuks- ezofagite, Zollingera- Ellison syndrome.

     Assign inside of 0,04-0,08 g / day (2 admission).

     In chronic ulcers associated with Helicobacter pylori, pantoprazol used in combination with amoxicillin (1 g, 2 times daily) and klaritromitsinom (0.5 g, 2 times daily) or metronidazole (0.5 g, 2 times daily) and klaritromitsinom . The course of treatment seven days.

     Possible side effects : neuralgia, increasing transaminaz, headache, drowsiness or insomnia, swelling, impotency, allergic reactions, etc.

     The drug is contraindicated in severe renal failure.

     Product : pills kishechnorastvorimye to 0.02 and 0.04 g (20 and 40 mg) (No. 7, 14, 28).

     Storage : List B.

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