PANTOGAM (Pantogamum).

     CALCIUM salt D (+) - a, g-dioksi- b, b-dimelbutiril- - aminomaslyanoy acid, salt or limestone D (+) - gomopantotenovoy acid.

     Synonyms : Calcium homopantothenat, Hopaten.

     This acid is known : Acidum homopantenicum, Homopantothenic acid, HOPA, Hopatenic acid, Hopate.

     The white crystalline powder. The easily soluble in water, very little is soluble in alcohol; PH 5% aqueous 7, 0, 9, 0.

     On Pantogram chemical structure can be viewed as modified molecules pantotenovoy acid (see), which includes the balance of GABA, which replaces the block-alanine.

     On pharmacologically Pantogram also presents similarities with GAMK and pantotenovoy acid.

     The drug has elements nootropnoy activity improves metabolic processes, increases the body's resistance to hypoxia has protivosudorozhnoe influence of barbiturates lengthens, reduces response to pain irritation. He has no significant impact on Bioelectrical brain activity in peripheral adrenogenital and holinoreaktivnye system, characterized by short-moderate anti-hypertensive effect. Diluted malotoksichen.

     In a clinical study found that Pantogram improve the condition of patients with cerebral insufficiency ekzogenno- organic genesis, reduces motor anxiety, causes mental and physical fitness activities. It is also effective in giperkineticheskih disorders, epilepsy dzheksonovskoy, parkinsonizme, tremor, with neuroleptic syndrome, RAE form of abductions of children.

     Applied Pantogram children with mental deficiency, mental retardation and delayed language development, as well as (in the adjuvant therapy, and sometimes myself) with epilepsy, especially in small polymorphic attacks or seizures fits.

     There are performance pantogama (decrease pain) in the chamber troynichnogo nerve (see also oxybutyrate Sodium).

     Assign Pantogram also integrated with convulsants means with epilepsy include events sunk in CNS skull and brain injuries.

     Applied also in subcortical giperkinezah, including (as proof) with neurotic ekstrapiramidnom syndrome. From prevention to be appointed along with neyrolepticheskimi means.

     Is Pantogram inwards (within 15 to 30 minutes after eating). Under the dose for adults is usually 0.5 to 1 g, for the children - 0.5 0.25-city daily dose for adults 1, 3, 5-g, 0.75 for children 3 g. The course of treatment lasts from 1 to 4 months (sometimes up to six months). After a 3-6-month break may be repeated treatment.

     Children with mental deficiency appoint 0.5 g 4 to 6 times a day. The course of treatment an average of three months.

     In epilepsy used (together with specific protivoepilepticheskimi means), children of 0.25 - 0.5 g 3 - 4 times a day for adults to 0.5 grams-1 3 - 4 times a day.

     In giperkinezah designate children of 0.25 - 0.5 g 3 to 6 times a day; Adult-to 0.5 g of 3 to 6 times a day.

     Using pantogama possible allergic responses (rhinitis, conjunctivitis, skin rashes). In these cases, medication overturned.

     Product : tablets for 0.25 and 0.5 g in a package of 50 pieces.

     Storage : dry, the dark place at room temperature.

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