NISTATIN (Nystatinum). 19-Mikozaminilnistatinolid.

     Is Antibiotic substance produced by Streptomyces aktinomitsetom noursei.

     Refers to antibiotics polienovoy group.

     Synonyms : Anticandine, Fungicidin, Fungistatin, Mikostatin, Moronal, Mycostatin, Nistatin, Nystafungin, Nystatin, Stamicin etc.

     Powder light yellow color with a specific smell, bitter-tasting, almost nerastvorim in water, very little of alcohol. Sensitive to the action of light, high temperature and oxygen air. Easily destroyed in acidic and alkaline media and the effects of oxidants. Gigroskopichen.

     Nystatin activity is expressed in units of (ED). At 1 mg product contains at least 4000 ED.

     Nystatin is to pathogens and fungi especially drozhzhepodobnye kind Candida fungi, as well as aspergilly; For bacteria inactive. Preparation is poorly absorbed; The bulk adopted inward, out of Cal.

     Nystatin applied for the prevention and treatment of diseases caused by fungi drozhzhepodobnymi kind Candida (Candida albicans, etc.); Candidiasis mucous membranes (mouth, vagina, etc.), skin and internal organs (gastrointestinal tract, lungs, kidneys, etc.) . From prevention to nominate to the development of candidiasis in long-term care drugs penicillin and other antibiotics, especially with oral antibiotics application tetratsiklinovogo series levomitsetina, neomycin, etc., as well as the weakened and depleted patients.

     Nystatin appointed interior tablets. Adults are at 500000 ED 3 to 4 times a day or 250,000 ED 6 to 8 times a day. Daily intake 1500000 3000000 - ED. In severe generalized candidiasis daily dose can be increased to 4 million-6 million ED. Children under the age of 1 year to designate 100000 - 125000 ED, from 1 to 3 years in the ED 250000 3 - 4 times a day; Over 13 years - from 1 million to 1.5 million a day in the ED 4 admission.

     The average length of treatment from 10 to 14 days. Pills proglatyvayut not liquid.

     When recurring chronic candidiasis and the report submitted to repeated treatments with a break between courses 2 - 3 weeks.

     When treating fungal disease mucous membranes and skin can be used nistatinovaya ointment.

     In candidiasis lower divisions ulcers in obesity and can be applied vulvovaginitah candles and globes, containing 250000 and 500000 ED. They are two times a day, the average rate of 10 to 14 days.

     Nystatin malotoksichen; Side effects usually greeted with extreme sensitivity to the antibiotic possible nausea, vomiting, diarrhea, increased body temperature, vomiting, etc. In such cases, reduce the dose.

     Method of production : tablets, coated yellow, containing 250000 and 500000 ED; Candles and vaginal suppositories of 250000 and 500000 ED; In ointment tubes containing 100000 ED of nystatin in 1 year

     Storage : List B. In dry, the dark place at a temperature of not more than +  5 C.

     Ointments nistatinovaya (Unguentum Nystatini). Ointments yellow. Includes 1 g 100000 ED nystatin.

     Assign to fungal diseases of skin and mucous membranes, especially in defeat drozhzhepodobnymi mushroom type Candida. Effective in fungal complications from the use of antibiotics. Masi Applications can be combined with the admission of nystatin inside.

     Product : in the box on 15 and 30 C.

     Storage : List B. In a cool place.

     Rp. : Tab. Nystatini obductae 250000 ED N. 40

     D.S. On March 2 tablets 4 times a day

     Rp. : Ung. Nystatini 15 0

     D.S. Outdoor

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