Norsulfazol (norsulfazolum)
NORSULFAZOL (Norsulfazolum). 2 - (para-Aminobenzolsulfamido) - tiazol.
Synonyms : Amidotiazol, Aseptosil, Azoseptale, Cibazol, Eleudron, Poliseptil, Pyrisulfon, Sulfathiazole, Sulphathiazolum, Thiazamide and others.
White or white to slightly yellowish sheen crystalline powder and odourless. Very little is soluble in water, dry in alcohol, divorced soluble in mineral acid and caustic solutions and carbon alkalis.
Norsulfazol effective in infection caused by haemolytic streptococcal, pneumococcal, gonokokkom, Staphylococcus, and coliform bacilli.
The drug is readily absorbed from the gastrointestinal tract and rapidly out from the body. Write mainly with urine, mainly in a free, neatsetilirovannom form.
Applied inside with pneumonia, meningitis, sepsis and streptococcal sepsis and other infectious diseases. When pneumonia and meningitis are designated adult admission for the first 2 g, followed by 1 g every 4 to 6 h to reduce body temperature; Continue to take 1 g every 6 to 8 hours Total treatment for a patient is a 20-ZO g drug. When staphylococcal infection first appointment designate 3 to 4 g, and then to 1 g four times a day. The course of treatment continues 3 to 6 days. Patients dysentery drug appointed as sulfadimezin (see).
Children norsulfazol designate a 4-6 - 8 hrs in the following single doses : at the age of 4 months to 2 years - to 0.1 - 0.25 g, 2 to 5 years 0.3 - 0.4 grams of 6 to 12 years - to 0.4 - 0.5 g. On the reception given double dose.
Higher doses for adults inside : single 2 g daily 7 g.
In applying norsulfazola to support enhanced Diurez (Administration of the day for 2 - 3 litres : after each receiving drug drinking one glass of water with the addition of 1 / 2 teaspoon of sodium gidrokarbonata borzhoma or glass).
The drug is usually well tolerated, but can occur in rare cases, vomiting.
The advent of chemotherapy more effective means of norsulfazola relatively limited.
Method of issuance : powder; Tablets of 0.25 and 0.5 g in a package of 10 pieces.
Storage : List B. The well ukuporennoy packaging.
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