NELFINAVIR (Nelfinavir).

     (3S, 4aS, 8aS) -N- Butil-2- tert-[(2R, 3R) -3 - (3,2-krezotamido) -2 - oksi-4- (feniltio) butyl] dekagidro-3- izohinolin- karboksamida Methanesulfonate.

     Synonym : Virasept, Virasept.

     Active against HIV-1 protease and VICH-2.

     Quickly and almost entirely (80% of dose) absorbed in the digestive tract, A max is 2-4 h, T? h-2,5-5; biotransformation exposed in the liver, appears mostly in faeces.

     Applied in the treatment of HIV infection.

     Assign inside adults and children over 13 years of 0.75 grams of children up to 13 years at a rate of 20-30 mg / kg 3 times a day.

     Possible side effects : diarrhoeal phenomenon, disruption of the liver, neutropenia.

     Contraindicated in pregnancy and breastfeeding.

     Method of production : tablets of 0.25 g (N. 180, 270), in vials of powder 144 g (0.05 g product in 1 g), complete with historical spoons.

     Storage : List B.

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