Sodium thiosulfate (natrii thiosulfas)
SODIUM TIOSULFAT (Natrii thiosulfas) (See also Magnesium sulfate).
Synonyms : Sodium hypo, Natrium hyposulfurosum, Natrium thiosulfuricum.
Clear transparent crystals odourless, solonovato- bitter to the taste. Very easily soluble in water (1:1), almost nerastvorim of alcohol. With the temperature around 50 + 'S melts in the water of crystallization.
An aqueous solution (30%, pH 7, 8, 8, 4) are sterilized at a temperature of 100 + 'C for 30 min (1 l of solution added 20 g sodium gidrokarbonata).
Sodium thiosulfate has protivotoksicheskoe, desensibiliziruyuschee and antiinflammatory effects.
As protivotoksicheskoe tools used in the administration of compounds of arsenic, mercury, lead (sulphites are non-toxic), cyanide, and its salts (formed rodanistye less toxic compounds), salt iodine, bromine.
Enter intravenously for 5-30% 10 ml solution, with the defeat of cyanide compounds -- 50% 30 ml solution. Inside appointed to 2 - 3 g per reception in a 10% solution in water or isotonic sodium chloride solution.
Assign also intravenously and in the interior of allergic diseases, arthritis, neuralgias.
External used for the treatment of scabies patients (see also Benzilbenzoat) method Demyanovicha based on the ability of sodium thiosulphate disintegrating in the acidic environment, providing sulphur and sulphur dioxide, providing antiparasitical effect. In skin rubbing 60% solution of sodium thiosulfate (consistently for 2 to 3 minutes in the left and right upper limbs, torso, left and right lower limbs, all within 10 to 15 minutes). After the stabbing, make a break for a few minutes to dry skin and the appearance of its ice. Then make the same sequence in the second round of cement. After drying the skin, rubbing 6% solution of hydrochloric acid, Plucker at the Palm, in the same way 3 - 4-fold within 10 to 15 minutes prior to drying solution on the skin after each pepper. Washing allowed 3 days.
Method of issuance : powder; 30% solution in ampoules to 5; 10 and 50 ml.
R p. : N and 10.0 trii thiosulfatis
Q. A destill. 100 ml
M.D.S. Inside 1 - 2 table spoons in 5 to 10 minutes
R p. : Sol. Natrii thiosulfatis 5 ml 30%
D.t.d. N. 6 in a mpull.
S. At 5 ml in the vein. Enter slowly.
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