NAFAZOLIN (Naphazoline)

     Chemical name : 4,5-Digidro-2- (1-naftalinilmetil) -1H- imidazol (in the form of nitrate or hydrochloride)

     Description : Black or white with a yellowish sheen crystalline powder and odourless. It is soluble in water, soluble in alcohol, acetone soluble in little, very little in chloroform, almost nerastvorim in hexane.

     Pharmacology : The drugs act-sosudosuzhivayuschee.

Institute alfa1- and alfa2- adrenoretseptory is vazokonstriktsiyu increases AD, narrow tail, has anti - (anti) properties. Sosudosuzhivayuschy effectiveness of the treatment in a local application on mucous lining the nose and eyes (comes in a few minutes and lasts for a few hours). In rhinitis nasal breathing easier, reducing the flow of blood to the venous sine.

In a lengthy appointment of gradually decreasing (tolerance), and after 5-7 days of a break for a few days.

     Applications : acute rhinitis, pollinoz, sinusitis, nasal, laryngitis, evstahiit, nasal bleeding, allergic conjunctivitis; Rinoskopiya (in combination with mestnoanesteziruyuschimi means).

     Contraindications : Giperchuvstvitelnost, zakrytougolnaya glaucoma, hypertension, tachycardia, expressed atherosclerosis, severe eye disease, diabetes, Ray, chronic rhinitis, chest age.

     Side Effects : mucous membrane irritation, reactive hyperemia, in long-term use, swelling of mucous membrane; Nausea, headache, increased AD, tachycardia.

     Networking : Zamedlyaet suction mestnoanesteziruyuschih funds. Tricyclic antidepressants, Maprotiline heighten the effect.

     Overdosing : Symptoms : lowering body temperature, aetiology, hypertension.

Treatment : symptoms.

     Dosing and Administration : Intranasal; When rhinitis : adult-0,05-0,1 drops to 1-2% solution in each nostril, 2-3 times a day for children aged 1 year to 1-2 drops 0.05 % or even more diluted with distilled water solution.

When bow krovotecheniyah : a cavity in the nose tampons, soaked 0.05% solution.

When conjunctivitis : intrakonyunktivalno 1-2 drops 0.05% solution.

In rinoskopii to prolong the surface anaesthesia : 2-4 drops of 0.1% solution of 1 ml of anaesthetics.

Materials allowed to copy only with the active hyperlink to the handbook of medicines