NAKOM (Nakom).

     To reduce side effects and enhance the therapeutic action of L-Dov developed preparations containing L-Dov, along with peripheral inhibitors (ekstratserebralnogo) decarboxylation L-Dov. One of these inhibitors is carbidopa [gidrazinometildofa; 3-(3, 4-dioksifenil) -2 - gidrazino-2- methyl-propionic acid].

     The combination of L-Dov with carbidopa leads to inhibition of decomposition L-Dov in the blood and peripheral tissues and enhance L-Dov in the tissues of the brain, where L-Dov into something. In connection with the possible use of lower doses of L-Dov, the faster a clinical effect and reduces the severity of adverse impacts.

     Indications for use Nacoma like to levodopa.

     Assign feature inside at the time, and after a meal. Dose choose individually to the characteristics of the principal component (levodopa). Usually admission starting from 1 / 2 - 2 1 pill twice a day; If necessary, increase the daily dose, adding 1 / 2 tablets every 2 to 3 hours until the optimum effect (usually 3 to 6 pills a day, but not more than 8 the tablets a day).

     Patients who had received prior L-Dov be before treatment nakomom stop (not less than 12 hours) received L-Dov, a feature taken in the early days in small doses (no more than three tablets per day). Supporting dose for most patients is 3 to 6 pills a day (no more than 8 tablets per day).

     Precautions and contraindications when applying Nacoma are the same as for the L-Dov (levodopa).

     Product : pills containing 0.25 grams (250 mg) levodopa and 0,025 g (25 mg) karbidona, in a package of 100 pieces.

     A similar product is available under the name <<Sinemet>> (<<Sinemet >>*).

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