NABUMETON (Nabumetone).

     4 - (6-Methoxy naphthyl) -2 - butanone.

     Synonyms : Relafen, Rodanol S, Relafen, Rodanol S.

     White or colourless crystalline powder. Nerastvorim in water, soluble in alcohol or other organic solvents.

     On chemical structure and antiinflammatory activity close to naproksenu. (see).

     Has antiinflammatory, blood analgesic and antipyretic effects.

     When ingestion rapidly and completely absorbed, bioavailability of 80%, T1 / 2-24 hours; Biotransformation are in the liver, kidneys displayed.

     Applied with rheumatoid arthritis and osteoarthritis.

     Assign inside (regardless of meal times) and 1 g 1-2 times a day.

     Possible side effects are basically the same as when applying naproksena. Ultserogennoe expressed less effect.

     Contraindications to stomach ulcers and duodenal ulcers (as in the acute period, and the anamnesis), bronchial asthma, heart failure, peripheral oedema, violations of liver and kidney hemophilia.

     Anti enhance effects, and antiagregantov fibrinoliticheskih drugs, as well as the side effects of glucocorticosteroids.

     Product : pills to 0.5; 0.75 and 1 g (N. 20, 100).

     Storage : List B.

Materials allowed to copy only with the active hyperlink to the handbook of medicines