MIKOGEPTIN (Mycoheptinum). 7-Digidro-5- degidrokandidin.

     Polienovy antibiotic produtsiruemy aktinomitsetom Steptoverticillium mycoheptinicum.

     The structure is close to amphotericin B B.

     Powder dark yellow without smell and taste. Sensitive to light and elevated temperature inaktiviruetsya in Action-acids and alkalis. Almost nerastvorim in water, very little is soluble in alcohol.

     The drug is active against pathogens profound systemic mycosis drozhzhepodobnyh and mushrooms.

     When ingestion partially absorbed; Presented with urine.

     The drug has a therapeutic effect in emerging mycosis. When applied koktsidioidoze, histoplasmosis, cryptococcosis, aspergilleze, candidiasis and some other mycosis.

     Assign inside of 0.25 g (ED 250000), 2 times a day for 10 to 14 days. With good endurance can be repeated courses.

     To treat the external manifestations of mycosis (mezhpaltsevye erosion heylity, destruction and outer skin folds, genitalia, etc.) apply ointment containing 1 g of 15 mg (15,000 ED) mikogeptina. Ointments cause for the affected areas of skin 1 to 2 times a day. The course of treatment 10 to 15 days. If necessary, treatment can be repeated. Ointments can be used alone or in conjunction with the admission of tablets or capsules mikogeptina inside.

     For admission into possible drug violations of kidney and gastrointestinal tract. Treatment should be under the control of residual nitrogen in the study of blood and urine. When the residual nitrogen levels more than 28, 6 mmol / L or a protein in the urine and pathological elements, as well as detecting expressed diarrhoeal disorders receive drugs to stop the disappearance of these changes.

     In the case of allergic reactions (skin, nausea, itching of the skin) designate protivogistaminnye drugs, with diarrhoeal events (nausea, abdominal pain), the interior solution novocaine.

     Repeating complications treatment mikogeptinom stop.

     The drug is contraindicated in violation of the kidneys and liver, acute gastrointestinal tract negribkovoy etiology, individual mikogeptina intolerances.

     Ointments should not be used if there is traumatic surfaces, abundant separated.

     Product : tablets, coated yellow, containing 50000 and 100000 ED mikogeptina pack of 40 pieces.

     Storage : List B. In dry, the dark place at a temperature not exceeding +  4 C.

Materials allowed to copy only with the active hyperlink to the handbook of medicines