MONOMITSIN (Monomycinum).

     Antibiotics, which is a mixture of sulfates organic basis produtsiruemogo Actinomyces circulatus monomycini var.

     On antibacterial properties and chemical structure similar to paromomitsinu : to antibiotics neomitsinovoy Group (aminoglikozidam).

     Powder or porous mass cream color. The easily soluble in water, virtually nerastvorim of alcohol.

     Drug activity is expressed in units of action; 1 ED activity with 1 µ g monimitsina grounds. Almost 1 ml containing 720 ED.

     Monomitsin active against gram and many gram bacteria [staphylococci, dysentery bacilli, Escherichia coli, Klebsiella wand (wand Friedlander), etc.] is weak at pnevmokokki and streptococci; Protea sensitivity varies widely depending on the strain. At the anaerobic flora, pathogenic fungi and viruses is not operating.

     At sensitive to the micro monomitsin has bactericidal effect.

     Monomitsin has the ability to suppress the development of the simplest : the cause of cutaneous leishmaniasis, toksoplazmy, dysenteric amoeboids etc.

     Applied monimitsin inside, intramuscularly, in the cavity, the field.

     When injecting a drug quickly enters the bloodstream, well into the organs and tissues. When ingestion absorbed poorly, most of the drugs available to Cal.

     Monomitsin efficient at number enteritis, toxic neuralgia, bacillary and amoebic dysentery, salmonellosis, as well as acute and chronic urinary tract infection routes (mild and severe, without violating renal excretory function). The major indication for use monomitsina cutaneous leishmaniasis is.

     Assign an adult on the inside of 0.25 g (ED 250000), 4 to 6 times a day for children weighing up to 15 kg-10 - 15 mg / kg / day (2 - 3 reception at intervals of 8-12 h) . Children may be nominated in the interior of the solution. By dissolving drug for boiled water at the rate of 5000-10000 ED in 1 ml; The solution is to add sugar syrup. Rising water and milk.

     When heavy septic processes monomitsin happened intramuscularly; An adult dose of 0.25 g (250000 ED) three times daily, children 4-5 mg / kg / day (3 admission). Diluted dissolve 4-5 ml of 0.5% solution of novocaine or sterile water for injection. In peritonitis impose additional bryushnuiyu cavity 0.25 - 0.5 g of 5 to 10 ml of 0.5% solution of novocaine 1 every day. Duration of treatment no more than 5-7 days. In related pneumonia using more drugs penicillin.

     When treating cutaneous leishmaniasis monomitsin can enter a period of 10 to 12 days, subject to monitor kidney function and the hearing. You may need to appoint a local 2 - 3% ointment (prepared in the pharmacy).

     Treatment monomitsinom be conducted under the close supervision of a physician. With long-term use drugs may audible inflammation and nerve damage to the kidneys.

     In oral application monomitsina may have indigestion, nausea, vomiting.

     Like other antibiotikam- aminoglikozidam, monomitsin has nefroi neurotoxic effects; He is rotivopokazan with pneumonia hearing nerve and kidney functions violations.

     It is absolutely contraindicated parenteral use monomitsina with streptomycin, digidrostreptomitsinom, kanamycin and other nefro- and ototoksichnymi antibiotics. Successive treatments these antibiotics can be made only after an interval of at least 14 days.

     Pregnant designated only for special reasons and with great caution.

     Method of issuance : in the hermetically ukuporennyh bottles of 0.25 and 0.5 g (250000 and 500000 ED); Pills to 0.25 grams in a package of 10 pieces.

     Storage : List B. In dry, the dark place at room temperature.

Materials allowed to copy only with the active hyperlink to the handbook of medicines