MOLSIDOMIN (Molsidominum) *.

     N-Ethyl ether karboksi-3- morfolino- sidnonimina.

     Synonyms : Korvaton, Sidnofarm, Corvaton, Molsidomin, Morial, Motazomin, Sydnopharm.

     White kristallichessky powder.

     On molsidomin chemical structure is similar to psychotropic drugs sidnokarbom (see) and sidnofenom (see). But psychotropic activity it does not have and is an active peripheral vazodilatatorom. It reduces storage peripheral vascular tone (venul) and venous flow to the heart. Influenced molsidomina lowered pressure in the pulmonary artery decreased filling the left ventricle and the heart wall stress, as well as the crash of. Kollateralny preparation improves blood flow and reduces the aggregation of platelets.

     Vazodilatatornoe of molsidomina probably to some extent a result of his group NO molecules that kinship with nitrite and sodium nitroprussidom (see).

     Applied molsidomin antianginalnoe primarily as a means to prevent strokes. In these cases, it took the inside (in the form of tablets 2 mg). Step similar mainly of nitrogen. Relatively nitrosorbidom with, the effect is somewhat earlier, but the total of slightly less.

     For cupping the strokes sometimes designate molsidomin sublingvalno.

     In applying molsidomina in adjuvant therapy cardiopulmonary diseases reached reduce pulmonary hypertension and improve hemodynamics.

     Inside are molsidomin for 1 to 2 mg (1 / 2 - 1 tablet) 2 - 3 - 4 times a day after meals.

     Sublingvalno appoint 1 / 2 - 1 pill.

     With sublingual application is caused by 5 - 10 minutes when administered through 20 minutes.

     By molsidominu compared with organic nitrates in the less developed tolerance.

     Before the drug can headache and a slight reduction in AD, passing the reduced dose. Some patients molsidomin moved better than nitrates.

     Contraindications : kardiogenny shock and severe hypotension. In severe heart attack drug can be granted only under strict control. Do not use drugs in the first three months of pregnancy.

     Product : pills to 0,002 grams (2 mg) in a package of 40 pieces.

     Storage : List B. In the dark spot.

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