MINOKSIDIL (Minoxydin) *. 2, 4-Diamino-6- piperidinopirimidin-3- oxide :

     Synonyms : Rigeyn, Loniten, Lonolax, Lonoten, Prexidil, Regaine.

     Has peripheral vazodilatatornoe act expands resistant receptacles (arterioly); AD reduces system, reduces the burden on the attack.

     I think that salts and the anti-hypertensive effect minoksidila due to the fact that he is agonist (discovered) potassium channels in vascular smooth muscle (see Gipotenzivnye means).

     Applied mainly in the form of heavy hypertension resistant sosudorasshiryayuschim other means. Usually designate combined with b-adrenoblokatorami and diuretikami.

     Is inside. Initial dose of 0,005 grams (5 mg) per day with a gradual increase its (every 2 to 3 days) for 2, 5 - 5 mg / day to stabilize the AD (10-25 mg per day with a further gradual reduction in dose) . The daily dose given in two reception and an 12 hours

     Feral production : tablets of 0,005 grams (5 mg).

     In applying minoksidila was established that during a drug to serve a growing hair growth. Therefore, the company that produces minoksidil ( "cleared"), was issued a special product for local use-rigeyn (regeyn) containing 2% minoksidila (20 mg minoksidila in 1 mL of 60% ethanol with the addition of propylene and water). Prepararat cause of the affected areas head 1 ml 2 times a day (morning and evening), regardless of the area affected. Treatment for long-term (up to 1 year or more). A significant portion of patients with disease duration of no more than 3 to 5 years, the benefit.

     Ongoing studies on the effectiveness and acceptability of the drug.

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