MILRINON (Milrinone) *. 1, 6-Digidro-2- metil-6- Okseo [3 4'- bipiridin] -5 - karbonitril.

     Available in the form of lactate.

     Synonym : Primacor.

     The structure and action close to amrinonu. Instead of helping men amino group of N and P are additional metilny substituent. More active than amrinon and better postponed.

     It is (like amrinonu) only for short-term treatment of acute heart failure. Enter first intravenous ( "loading dose") at the rate of 50 µ g / kg (0.05 mg / kg) for 10 minutes (about 0.5 ug / kg / min). Supporting dose-0,375 - 0.75 µ g / kg per minute up to a total dose of 1, 13 mg / kg per day.

     Length of depending on the effect of 48-72 h.

     Possible side effects : hypotension, pain in the heart, gipoka liemiya, adults.

     Contraindications after acute myocardial infarction in pregnancy.

     Treatment must be carefully haemodynamic Contra grievances. If the kidney function appointed in small doses. In gipokaliemii should make preparations potassium.

     Product : 0.1% solution in ampoules and 10 ml (10 mg).

     An oral form of the drug.

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