Midekamitsin (midecamycin)


MIDEKAMITSIN (Midecamycin).
     Synonym : Makropen, Macropen.
     Antibiotics group macrolides.
     It has a wide range of activity. Active against gram (staphylococci, streptococci, cause diphtheria, listerii, etc.) and gram (Helicobacter, Campylobacter, Haemophilus wand, etc.) bacteria, anaerobov (bakteroidy, receiver) and intracellular pathogens (mycoplasma, chlamydia and legionelly etc.).
     Once inside quickly and completely absorbed, with max of 1-2 hrs; Accumulates in the lungs, tumors and podchelyustnoy gland, skin; Biotransformation exposed in the liver, bile appears mainly.
     Applied with infection of the respiratory tract and urinary tract caused by the intracellular microorganisms; Infections of the respiratory tract, skin and subcutaneous tissue caused by bacteria susceptible to penicillin; When enteritis caused by kampilobakterom and for the treatment and prevention of whooping cough and diphtheria.
     Assign an adult on the inside of 0.4 g three times per day, children 20-50 mg / kg (2-3 admission). The course of treatment for 7-10 days (with chlamydial infection, 14 days).
     Possible side effects : diarrhoeal phenomenon, eosinophilia, allergic skin reactions.
     The drug is contraindicated in severe liver failure.
     Method of issuance : pills to 0.4 g (N 8); Powder for 3.5% suspension for receiving inside.
     Storage : List B.

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