Meksidol (mexidolum)


MEKSIDOL (Mexidolum). 3-methyl Oksi-6- etilpiridina succinate.
      White or white with a white crystalline powder kremovatym. The easily soluble in water.
      On chemical structure is appropriate meksidol emoksipinu amber acid salt (suktsinatom).
      Like emoksipinu, meksidol an inhibitor free radical processes (antioxidant), but has a stronger antihypoxia action.
 
      Meksidol has a wide spectrum of biological activity. It is effective in different types of hypoxia : providing a stronger and longer effect than BHT (BHT). The drug increases the body's resistance to kislorodzavisimym pathological condition (shock, a violation of cerebral circulation, etc). , Improves mnesticheskie functions reduces toxic effects of alcohol and others.
      Meksidol proposed for the treatment of acute disturbance of cerebral circulation, distsirkulyatornoy encephalopathy, vegetososudistoy dystonia, ateroskleroticheskih violations of brain edema for GHB with alcohol syndrome and drug addiction, and other states, accompanied by tissue hypoxia.
      Applied meksidol intramuscularly or intravenously (struyno drip). Struyno product should enter cravings for edema syndrome and vegetation and simpatoadrenalovyh epileptic, and drip with severe violations of cerebral circulation.
      When intravenously as a solvent to use sterile water for injection. Struyno meksidol imposed for 5 to 7 minutes, drip at speeds of 60 drops per minute. Dose nominated individually.
      Started treatment with 100 mg dose of 1 to 3 times a day, gradually increasing the dose until a therapeutic effect. Duration of treatment and selection of individual doses depend on the seriousness of the patient and treatment. The maximum daily dose should not exceed 800 mg.
      For the treatment of severe violations of cerebral circulation (stroke), meksidol designate intravenous drip in the dose of 200 mg-300 in the first two to four days, and then 100 mg intramuscular injection three times a day.
      Patients with distsirkulyatornoy encephalopathy and vegetososudistoy dystonia drug impose intramuscularly in 50-dose 100 mg three times a day.
      When opioid syndrome meksidol imposed on the dose of 100 to 200 mg intramuscularly 2 - 3 times daily or intravenously (drip) 1 to 2 times daily, as neurotic disorders and gets appointed by intramuscular injection dose of 50 to 400 mg per day.
      For ateroskleroticheskogo treatment of dementia in patients older meksidol applied dose intramuscular injection of 100-300 mg per day.
      In acute intoxication neurotic struyno intravenous drug use in 50-dose 300 mg per day.
      Usually meksidol well tolerated. Some patients may cause nausea and dry mouth.
      The drug is not suitable for violations expressed in liver function and kidney with a history of allergy to pyridoxine (vitamin B 6) [of the chemical structure is similar to meksidol pyridoxine (see).
      Product : 5% solution in 2 ml ampoules.
      Storage : List B. In the dark spot.

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